Abstract
The aim of this case-control study was to carry out an oral health assessment on a group of Alzheimer's patients and to establish a hypothesis regarding the implication of the characteristics of the disease and the treatment of oral health. A total of 70 Alzheimer's patients, residents at the Alzheimer Center Reina Sofia Foundation (Madrid, Spain) and at the Alzheimer State Reference Center (Salamanca, Spain), and 36 controls (companions/acquaintances), were studied by oral examination and saliva sampling. The oral health indices DMFT/DMFS, CPI, the prosthetic condition, oral hygiene, saliva volume, and pH, as well as the specific microbiological parameters governing the risk of developing caries were assessed. Alzheimer's patients exhibited, as compared to the control group, (1) fewer teeth (10.9 ± 10.5 vs 23.7 ± 6.5), (2) fewer obturations (2.2 ± 3.4 vs 6.6 ± 5.6), (3) fewer periodontally healthy sextants (0.1 ± 0.4 vs 1.4 ± 2.2), (4) worse oral hygiene (43.1 vs 72.2% brushed), (5) greater use of removable prostheses (47.8 vs 8.4%), (6) higher incidence of candida infection (11.8 vs 0.0%) and cheilitis (15.9 vs 0.0%), (7) lower salivary flow (0.6 ± 0.6 vs 1.1 ± 0.6), and (8) lower buffering capacity (46 vs 80%). After taking ...Continue Reading
References
Jan 1, 1989·Gaceta sanitaria·A Domingo Salvany, J Marcos Alonso
Feb 1, 1983·Infection and Immunity·I ZickertB Krasse
Jan 1, 1994·Journal of the American Geriatrics Society·J A Ship, S A Puckett
Jun 21, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Hümeyra KocaelliHakan Ozbas
Jul 2, 2004·The New England Journal of Medicine·Jeffrey L Cummings
Jun 30, 2005·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Kathleen Dobrosielski Vergona
Sep 1, 2005·Community Dentistry and Oral Epidemiology·Pilar Ruiz-MedinaJavier Montero
Sep 2, 2006·The Journal of the American Dental Association·Arthur H FriedlanderJohn A Yagiela
Nov 30, 2006·Alzheimer Disease and Associated Disorders·Mary SanoUNKNOWN Alzheimer's Disease Cooperative Study Group
Feb 17, 2007·Gerodontology·Fernando Neves HugoRenato José De Marchi
Oct 3, 2007·The Journal of the American Dental Association·Pamela Sparks SteinRichard J Kryscio
Oct 22, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Lena N TurnerEric T Stoopler
Mar 10, 2009·Dental Clinics of North America·Robert G Henry, Barbara J Smith
Nov 4, 2009·The Journal of the American Dental Association·Birita EllefsenGunhild Waldemar
Mar 6, 2010·Acta Neuropathologica·Kurt A Jellinger, Johannes Attems
Mar 27, 2010·Gerodontology·Soraya Coelho LealPedro Zanotta
Jul 8, 2010·Gerodontology·Anna-Maija Hannele SyrjäläMatti Knuuttila
Nov 9, 2010·Gerodontology·Müjgan Güngör HatipogluGül Güven
Dec 15, 2010·Journal of the American Geriatrics Society·Xi ChenJia Xu
Apr 26, 2011·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Guy M McKhannCreighton H Phelps
Nov 9, 2011·Community Dentistry and Oral Epidemiology·E ArrivéJ F Dartigues
Mar 31, 2012·Gerodontology·Ashita S UppoorDilip Nayak
May 1, 2012·Gerodontology·Birita S EllefsenPoul Holm-Pedersen
Aug 7, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Giselle Rodrigues RibeiroRenata Cunha Matheus Rodrigues Garcia
Jun 5, 2013·Journal of the American Geriatrics Society·Hae-Ra HanHochang Ben Lee
Oct 10, 2013·Korean journal of family medicine·Joong Soo KimHyun Rim Choi
Jun 21, 2014·Journal of Alzheimer's Disease : JAD·Sim K SinghraoStJohn Crean
Sep 10, 2014·Dental Clinics of North America·Leonard J Brennan, Jason Strauss
Dec 20, 2014·Journal of the American Geriatrics Society·Georgios TsakosPanayotes Demakakos
Jul 23, 2015·North American Journal of Medical Sciences·Keshava AbbayyaY S Chidambar
Citations
Dec 12, 2018·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Fatemeh Ahmadi-MotamayelMehrangiz Vahabian
Jan 3, 2020·Current Opinion in Psychiatry·Matthew R Nangle, Nithin Manchery
Feb 15, 2020·Head & Neck·Rayan MrouehAntti A Mäkitie
Jan 19, 2019·Molecular and Clinical Oncology·Koji HaradaKatsuaki Mishima
Jul 6, 2020·Carcinogenesis·Shih-Chi SuShun-Fa Yang
May 6, 2019·Dentistry Journal·Mario DioguardiLorenzo Lo Muzio
Oct 1, 2020·Journal of Clinical Medicine·Joanna Samborska-MazurKatarzyna Błochowiak
Jun 11, 2020·Ciência & saúde coletiva·Ilky Pollansky Silva E FariasYuri Wanderley Cavalcanti
Apr 10, 2019·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Leonardo MarchiniAdina Jucan
Aug 11, 2020·Clinical Oral Investigations·Raquel de Oliveira AraújoEduardo Jorge Feres-Filho
Oct 27, 2020·International Journal of Geriatric Psychiatry·Liang-Nan ZengYu-Tao Xiang
Feb 12, 2021·Journal of the American Medical Directors Association·Jingyi ZhangXiang Liu
Mar 7, 2021·Journal of Clinical Medicine·Norishige KawanishiKatsuhiko Kimoto
Jun 11, 2021·Frontiers in Aging Neuroscience·María Olimpia Paz AlvarengaRafael Rodrigues Lima
Jul 3, 2021·International Journal of Environmental Research and Public Health·Haiying GuoMinquan Du
Jul 12, 2021·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Xin HuZhaonan Liu
Oct 13, 2021·Journal of Oral Biosciences·N T Desta