Oral hypertonic glucose solution in the treatment of infantile colic

Pediatrics International : Official Journal of the Japan Pediatric Society
Mustafa Akçam, Aygen Yilmaz

Abstract

Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC. A total of 25 infants diagnosed as typical IC were given 1 mL of 30% glucose solution or sterile water for 4 days consecutively, in a randomized, double blind crossover trial. The effect was measured by parents' scoring. Parents reported varying degrees of improvement in 16 infants (64%) given glucose solution, and in 12 infants (48%) given placebo. Comparison of treatment modalities were statistically significant (P = 0.031). There was no side-effect during treatments. The present study revealed that 30% glucose was effective in the treatment of IC. Since oral glucose solution is natural, safe, cheap and easily achievable, it might be considered as an alternative therapy.

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Citations

Sep 23, 2010·Current Opinion in Pediatrics·Francesco Savino, Valentina Tarasco
Jul 25, 2012·Italian Journal of Pediatrics·Abdelmoneim E M Kheir
Mar 1, 2012·La Presse médicale·Virginie Bruyas-BertholonLaurent Letrilliart
Nov 10, 2012·Nutrition·Yvan VandenplasPedro Alarcon
Dec 4, 2014·Beneficial Microbes·Y Vandenplas, P Alarcon
Oct 4, 2008·Clinical Pediatrics·Justine Cohen-Silver, Savithiri Ratnapalan
Sep 16, 2016·The Cochrane Database of Systematic Reviews·Elena BiagioliFrancesco Savino
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Dawn DobsonGeorge Lewith
Dec 15, 2015·Journal of Pediatric Gastroenterology and Nutrition·Tracy HarbRebecca Hill
Jan 22, 2011·Journal of Separation Science·Serkan Erdemir, Mustafa Yilmaz

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