Oral immunization with a combination of Plasmodium yoelii merozoite surface proteins 1 and 4/5 enhances protection against lethal malaria challenge

Infection and Immunity
Lina WangRoss L Coppel

Abstract

Oral immunization of mice with Escherichia coli-expressed Plasmodium yoelii merozoite surface protein 4/5 or the C-terminal 19-kDa fragment of merozoite surface protein 1 induced systemic antibody responses and protected mice against lethal malaria infection. A combination of these two proteins administered orally conferred improved protection compared to that conferred by either protein administered alone.

References

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Citations

May 10, 2005·Molecular and Biochemical Parasitology·Hannah E J PolsonShirley Longacre
Sep 19, 2006·Parasitology·A GomezM A Patarroyo
Nov 18, 2009·Infection and Immunity·E Elsa Herdiana MurhandarwatiRoss L Coppel
Nov 28, 2006·Medical Hypotheses·Alberto Pinzon-Charry
Apr 12, 2016·Journal of Dietary Supplements·Anjali AryamvallyRathinasabapathi Pasupathi
Oct 6, 2004·Expert Opinion on Biological Therapy·Lina WangRoss L Coppel
Jun 10, 2006·Hematology/oncology Clinics of North America·Rodica StanAdam D Cohen
May 18, 2007·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Mohd Azhar AzizRakesh Bhatnagar
Jul 31, 2008·Expert Review of Vaccines·Lina Wang, Ross L Coppel

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