PMID: 6411638Jun 1, 1983Paper

Oral leukoplakia: a scanning electron microscopic study of epithelial surface patterns

International Journal of Oral Surgery
P A Reichart, J Althoff

Abstract

Biopsies from oral leukoplakias of different anatomic locations were studied by light- and scanning electron microscopy. Clinically, 11 cases showed the homogenous, flat type, and 3 represented the inhomogenous, nodular type of oral leukoplakia. The surface patterns of lining epithelial cells, as well as the cut surface structures were compared with those obtained by light microscopy. The results were compared with other published findings of normal oral mucosa, oral leukoplakia, oral carcinoma, and lesions of the uterine cervical mucosa. The epithelial surface cells revealed micropatterns comparable to normal ortho- or parakeratotic cells in the cases of homogenous oral leukoplakia. Biopsies showing varying degrees of dysplasia revealed cell surfaces with irregular microvilli or swollen microridges; cell forms also showed varying profiles and shapes as well as pleomorphism. Cell desquamation was seen in all cases. Since cell maturation and differentiation is linked to a specific surface morphology, SEM has to be considered as a further valuable diagnostic method.

References

Jul 1, 1978·Journal of Periodontal Research·P Cleaton-JonesA Volchansky
Oct 1, 1978·Oral Surgery, Oral Medicine, and Oral Pathology·I R KramerL H Sobin
May 1, 1980·Journal of Oral Pathology·J BánóczyM Albrecht
May 1, 1980·Cancer·J J PindborgF S Mehta

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Citations

Nov 1, 1994·European Journal of Cancer. Part B, Oral Oncology·K R PillaiV P Menon
Jun 1, 1991·International Journal of Oral and Maxillofacial Surgery·P Jungell
Jul 28, 2015·Ultrastructural Pathology·P AsikainenA M Kullaa
Aug 21, 2013·Ultrastructural Pathology·Pekka AsikainenArja M Kullaa
Jan 1, 1996·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M D McMillan, A C Smillie
Dec 6, 2007·International Journal of Immunopathology and Pharmacology·F MastrangeloS Tetè

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