Oral malignant melanoma associated with pseudoepitheliomatous hyperplasia. Report of a case

Journal of Cutaneous Pathology
Marco MeletiIsaäc van der Waal

Abstract

Pseudoepitheliomatous hyperplasia (PEH), a histological mimic of squamous cell carcinoma, is an exuberant reactive epithelial proliferation that may be induced by a variety of infectious, traumatic, inflammatory and neoplastic conditions of the skin and mucous membranes. PEH has been described in association with Spitz nevi and intramucosal nevi but not with oral malignant melanoma. A case of PEH in malignant melanoma of the palate in a 46-year-old female patient has been described. A search of the English literature did not disclose any previously reported case of such event. PEH associated with oral malignant melanoma is apparently very rare and most likely originates from the surface epithelium. This is in contrast with PEH in cutaneous melanoma where follicular or eccrine units have been suggested to be the origin.

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Citations

Jul 11, 2009·The American Journal of Dermatopathology·Marie S TuttleStephen C Somach
Feb 11, 2010·The American Journal of Dermatopathology·Pascual AbenozaCarlos H Nousari
Mar 15, 2011·The American Journal of Dermatopathology·Maya Zayour, Rossitza Lazova
Oct 14, 2011·The American Journal of Dermatopathology·Jinane El-KhouryOssama Abbas
Jan 27, 2012·The American Journal of Dermatopathology·Angel Fernandez-Flores, Saul Valerdiz
Nov 4, 2010·Journal of Periodontology·Manojkumar ThoratBorse Pallavi
Aug 14, 2015·Journal of Cutaneous Pathology·Fumio IdeKaoru Kusama
Sep 22, 2009·Burns : Journal of the International Society for Burn Injuries·Du-yin JiangFei Shan
Oct 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Marco MeletiIsaäc van der Waal
Apr 24, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·Y KawachiF Otsuka
Aug 26, 2006·Oral Oncology·Marco MeletiIsaäc van der Waal
Feb 9, 2019·Journal of Cutaneous Pathology·Angela WipfDaniel Miller
Jul 18, 2012·The Journal of Craniofacial Surgery·Guolin XiangLihua Tian
Feb 11, 2015·The Journal of Craniofacial Surgery·Alimujiang Wushou, Ya-Jun Zhao
Apr 23, 2019·The American Journal of Dermatopathology·Andrea SagginiLorenzo Cerroni

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