Oral manifestations, salivary flow rates and Candida species in Thai HIV-infected patients

Journal of Clinical and Experimental Dentistry
Aroonwan Lam-UbolOitip Chankanka

Abstract

Effects of various Highly Active Antiretroviral Therapy (HAART) regimens on oral heath are unclear. Objectives: We aimed to evaluate effects of HAART on oral manifestations, salivary flow rates (SFR) and Candida species in HIV-infected patients who took mostly non-protease inhibitor-based HAART regimens. A cross-sectional study was performed on HIV-infected patients taking and never taken HAART who attended Thai Red Cross AIDS Research Centre (n = 48). Non-HIV subjects were recruited as control (n = 20). Oral conditions and salivary flow rates were evaluated using oral examination and measurement of unstimulated and stimulated saliva. In addition, Candida colonization counts (colony forming units; CFUs) and Candida species from the collected saliva were evaluated using CHROMagar. The most common oral manifestation in HIV-infected subjects taking HAART was hyperpigmentation. Unstimulated and stimulated SFR among the three groups were not statistically significant. Candida colonization was detected in 64%, 65% and 35% of HIV-infected subjects taking HAART, HAART-naïve, and non-HIV subjects, respectively. While 20% and 35% of HIV-infected subjects with and without HAART, respectively, had Candida CFUs higher than 500/ml, all non-H...Continue Reading

Citations

Jul 2, 2019·Oral Diseases·Supanat TarapanAroonwan Lam-Ubol
Aug 6, 2020·Journal of Family Medicine and Primary Care·Puneeta VohraRahul V C Tiwari
Nov 26, 2020·PloS One·Nada BuranaromOranart Matangkasombut

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