Oral quinolones in hospitalized patients: an evaluation of a computerized decision support intervention

Journal of Internal Medicine
T HulganD S Kernodle

Abstract

To determine whether a computerized decision support system could increase the proportion of oral quinolone antibiotic orders placed for hospitalized patients. Prospective, interrupted time-series analysis. University hospital in the south-eastern United States. Inpatient quinolone orders placed from 1 February 2001 to 31 January 2003. A web-based intervention was deployed as part of an existing order entry system at a university hospital on 5 February 2002. Based on an automated query of active medication and diet orders, some users ordering intravenous quinolones were presented with a suggestion to consider choosing an oral formulation. The proportion of inpatient quinolone orders placed for oral formulations before and after deployment of the intervention. There were a total of 15 194 quinolone orders during the study period, of which 8962 (59%) were for oral forms. Orders for oral quinolones increased from 4202 (56%) before the intervention to 4760 (62%) after, without a change in total orders. In the time-series analysis, there was an overall 5.6% increase (95% CI 2.8-8.4%; P < 0.001) in weekly oral quinolone orders due to the intervention, with the greatest effect on nonintensive care medical units. A web-based interventi...Continue Reading

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Apr 27, 2007·Pharmacy World & Science : PWS·Nada Atef SheblNick Barber
Dec 19, 2013·BMC Medical Informatics and Decision Making·Christopher L FillmoreKensaku Kawamoto
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