Oral Secondary Syphilis

Head and Neck Pathology
Peter N CarboneBrenda L Nelson

Abstract

Secondary syphilis develops in approximately 25% of patients infected with the spirochete bacterium Treponema pallidum. It typically develops several weeks to several months after the primary infection, which is recognized by a painless chancre. Secondary syphilis is characterized by systemic symptoms, such as malaise and fever as well as a maculopapular rash involving the trunk and extremities including the palms and soles. Condyloma lata, which are raised, fleshy lesions, tend to develop at the site of the primary chancre. Diagnosis is achieved primarily through screening and confirmational serologic testing. Histologic findings seen in condyloma lata are largely non-specific. Therefore, a high index of suspicion should be maintained and immunohistochemical stains specific for T. pallidum should be utilized.

References

Apr 9, 1999·Clinical Microbiology Reviews·A E Singh, B Romanowski

❮ Previous
Next ❯

Citations

May 8, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·N SugayaD Migliari
Jul 12, 2018·Stomatologii︠a︡·M A UfimtsevaT A Beresneva
Nov 26, 2019·Ear, Nose, & Throat Journal·Lester D R Thompson
Feb 21, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Clea Adas Saliba GarbinKarina Tonini Dos Santos Pacheco
Jul 28, 2019·Journal of Medical Case Reports·Kaitlyn L StreightDaniel M Musher
Jul 9, 2020·ACG Case Reports Journal·Shaheer SiddiquiScott Larson
Apr 28, 2020·Journal of the American Academy of Dermatology·Alexandre LamprosNicolas Dupin
Aug 4, 2021·Head and Neck Pathology·Frank DengJinping Lai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of the Medical Section of the Polish Academy of Sciences
J Kozakliewicz, T Wrzolkowa
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
H Schöfer
The Netherlands Journal of Medicine
S VeldhuisF N Lauw
© 2021 Meta ULC. All rights reserved