Oral sodium phosphate (Fleet) is a superior colonoscopy preparation to Picopre (sodium picosulfate-based preparation)

Diseases of the Colon and Rectum
J J TjandraPeter Tagkalidis

Abstract

Small-volume bowel preparation is better tolerated than 4-liter polyethylene glycol lavage. However, the efficacy of various small-volume bowel preparation agents for colonoscopy has not been clearly defined. This randomized, controlled trial was designed to compare oral sodium phosphate (Fleet) with Picoprep (sodium picosulfate-based preparation). Two hundred twenty-five outpatients, aged 65 years or younger, who would undergo colonoscopy by two endoscopists were randomized to receive two bottles of oral sodium phosphate or three sachets of Picoprep. A standardized questionnaire was completed by all patients and the endoscopists. The endoscopists were blinded to the preparation used. One hundred three patients were randomized to oral sodium phosphate (Fleet) (Group 1) and 122 patients to Picoprep (Group 2). Three patients were excluded because of colonic strictures. The groups were similar in age and gender, indications for colonoscopy, and previous colonic surgery. The quality of bowel cleansing in patients taking oral sodium phosphate (Fleet) was significantly better than Picoprep as assessed by the endoscopists (P = 0.0014). Both types of bowel preparation were associated with similar incidence of nausea (P = 0.4927), dizzi...Continue Reading

References

Jul 1, 1994·Diseases of the Colon and Rectum·S M CohenW B Ruderman
Jan 1, 1997·Diseases of the Colon and Rectum·D Frommer
May 28, 2004·Diseases of the Colon and Rectum·Joe J Tjandra, Peter Tagkalidis

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Citations

Sep 18, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A J RenautL Guilford
Jun 26, 2009·World Journal of Gastroenterology : WJG·Sasinee TongprasertSasivimol Rattanasiri
Feb 18, 2016·Surgical Infections·Donald E Fry
Mar 23, 2011·ANZ Journal of Surgery·Prasad J AthreyaGraham L Newstead
Nov 25, 2011·Alimentary Pharmacology & Therapeutics·J BelseyM Halphen
May 30, 2014·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jeong Bae ParkChang Heon Yang
May 31, 2008·The American Journal of Gastroenterology·Mahmoud SabriSeema Khan
Sep 18, 2007·Diseases of the Colon and Rectum·Jane J Y TanJoe J Tjandra
Dec 31, 2014·World Journal of Gastroenterology : WJG·Adolfo Parra-BlancoTakahiro Fujii
Aug 24, 2017·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Seok Won LeeDong Joon Kim
Oct 8, 2014·The American Journal of Gastroenterology

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