Oral vasodilators for primary Raynaud's phenomenon.

The Cochrane Database of Systematic Reviews
B Vinjar, Marlene Stewart

Abstract

Many different drugs have been suggested for the symptomatic treatment of primary Raynaud's phenomenon. Apart from calcium channel blockers, which are considered the drugs of choice, the evidence of the effects of alternative pharmacological treatments is limited. To assess the effects of various drugs with vasodilator actions on primary Raynaud's phenomenon. The Cochrane Peripheral Vascular Diseases Group searched their Specialised Register (last searched 24 July 2007), and the Cochrane Central Register of Controlled Trials (CENTRAL) (last searched Issue 3, 2007). In addition, we searched MEDLINE (January 1966 to July 2007), EMBASE (1980 to July 2007) and reference lists of relevant articles. We contacted pharmaceutical companies. There were no language restrictions. Randomised controlled trials evaluating the effects of oral formulations of any drug with vasodilator effects on subjective symptoms in primary Raynaud's phenomenon. Treatment with, or comparison with, calcium channel blockers was not assessed in this review. Both authors assessed the trials for inclusion and their quality. One author (BV) extracted the data MS checked the results. Data extraction included adverse events. we contacted trial authors for missing dat...Continue Reading

Citations

May 8, 2010·Vascular Health and Risk Management·Terri L Levien
Jul 13, 2012·The Cochrane Database of Systematic Reviews·Marlene Stewart, Joanne R Morling
Sep 16, 2010·Current Treatment Options in Cardiovascular Medicine·Soumya Chatterjee
Jan 10, 2012·Journal of Travel Medicine·Andrew J NealTimothy G Bennett
May 18, 2021·The Cochrane Database of Systematic Reviews·Kevin Yc SuJennifer Hwee Kwoon Ng
Nov 3, 2009·Seminars in Arthritis and Rheumatism·Amy Wasserman, Ernest Brahn

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