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Orb prevents autophagy in the Drosophila germline through translational repression of Atg12 mRNA

bioRxiv

Aug 15, 2014

Isabelle BusseauMartine Simonelig

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Abstract

Drosophila Orb, the homologue of vertebrate CPEB is a key translational regulator involved in oocyte polarity and maturation through poly(A) tail elongation of specific mRNAs. orb has also an essential function during early oogenesis which has not been addressed at the molecular level. ...read more

Mentioned in this Paper

Anatomical Maturation
Regulation of Translation
Cell Death
Homologous Gene
Mutant
CPEB1 protein, human
Chromosome 13q Deletion Syndrome
Vertebrates
Ovary
Genetic Translation Process
5
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  • Orb prevents autophagy in the Drosophila germline through translational repression of Atg12 mRNA

    bioRxiv

    Aug 15, 2014

    Isabelle BusseauMartine Simonelig

    PMID: 990007971

    DOI: 10.1101/007971

    Abstract

    Drosophila Orb, the homologue of vertebrate CPEB is a key translational regulator involved in oocyte polarity and maturation through poly(A) tail elongation of specific mRNAs. orb has also an essential function during early oogenesis which has not been addressed at the molecular level. ...read more

    Mentioned in this Paper

    Anatomical Maturation
    Regulation of Translation
    Cell Death
    Homologous Gene
    Mutant
    5

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