Orbital Apex Lesions: A Diagnostic and Therapeutic Challenge

Journal of Neurological Surgery. Part B, Skull Base
Sung-Woo ChoTae-Bin Won

Abstract

Objective  To analyze the clinical characteristics of and treatment outcomes for orbital apex lesions according to their pathological diagnosis and identify clinical characteristics that could aid in their differential diagnosis. Design  Retrospective analysis design was used for this study. Setting  The study was conducted in a single tertiary institution. Participants  Patients with pathologically confirmed lesions centered in the orbital apex who were admitted between January 2011 and December 2015. Main Outcome Measures  Clinical characteristics, including demographics, predisposing factors, presenting symptoms, radiological findings, intraoperative findings, biopsy results, and treatment outcomes. Results  Nine patients with invasive fungal sinusitis, six with inflammatory pseudotumor, and six with neoplastic or tumorous lesions were enrolled. The most common presenting symptom was orbital pain or headache, followed by ophthalmoplegia and vision loss, which exhibited overall recovery rates of 62.5% and 33.3%, respectively, after definitive treatment. The prognosis was worse for patients with invasive fungal sinusitis. There was no significant difference in age, underlying medical conditions, absolute neutrophil count, C-re...Continue Reading

Citations

Nov 19, 2019·Acta Oto-laryngologica·Lifeng LiDemin Han
Aug 28, 2020·Curēus·Joshua A RonenRaphael Nwojo
Oct 26, 2021·The Annals of Otology, Rhinology, and Laryngology·Andre J BurnhamLauren T Roland
Jul 8, 2021·Acta neurochirurgica·Felipe ConstanzoThomas Schmidt

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