Orbital granulocytic sarcoma in an elderly patient

American Journal of Ophthalmology
L M WatkinsPeter A D Rubin

Abstract

To report a 71-year-old woman with acute myelogenous leukemia in remission who developed orbital granulocytic sarcoma. The patient was referred for acute proptosis and decreased vision of the right eye. Computed tomography of the orbits demonstrated a right extraconal mass compressing the optic nerve. A right lateral orbitotomy was performed, and a portion of the mass was excised for diagnostic purposes and orbital decompression. Histopathologic and immunohistochemical evaluation disclosed orbital granulocytic sarcoma. With chemotherapy and radiation, vision remained stable and right proptosis resolved. Orbital granulocytic sarcoma is usually diagnosed in children with a history of acute myelogenous leukemia. This case demonstrated that this entity may also occur rarely in older patients with a history of acute myelogenous leukemia.

Citations

Apr 24, 2008·Pathology Oncology Research : POR·Erika MakaSándor Fekete
Feb 6, 2016·Journal of Medical Case Reports·Jesus Vera-AguileraCarlos Vera-Aguilera
Jan 3, 2013·International Journal of Cancer. Journal International Du Cancer·Maro OhanianZeev Estrov
Sep 29, 2012·Clinical Lymphoma, Myeloma & Leukemia·Maro OhanianNaveen Pemmaraju
Jan 15, 2013·Ophthalmic Plastic and Reconstructive Surgery·Patricia A Ple-plakonVictor M Elner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

AML: Role of LSD1 by CRISPR (Keystone)

Find the latest rersearrch on the ability of CRISPR-Cas9 mutagenesis to profile the interactions between lysine-specific histone demethylase 1 (LSD1) and chemical inhibitors in the context of acute myeloid leukemia (AML) here.

Related Papers

The Annals of Thoracic Surgery
M H Chamberlain, S A Nashef
Acta orthopaedica Belgica
Y Hallet, J Van Overschelde
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
B CanivetB Krebs
© 2022 Meta ULC. All rights reserved