Orbital implant exposure after Acanthamoeba panophthalmitis

American Journal of Ophthalmology Case Reports
Meredith S BakerRichard C Allen

Abstract

Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation. Eight months post-operatively, the patient developed orbital implant exposure secondary to persistent Acanthamoeba infection and underwent removal of the implant and aggressive, systemic treatment involving a multispecialty care team. He then underwent placement of a dermis fat graft and had no signs of persistent infection at the time of last follow-up, which was 24 months after placement of the dermis fat graft. and Importance: To the authors' knowledge, this is the first known case of Acanthamoeba infection causing orbital implant exposure. Persistent infection should be considered in Acanthamoeba patients who have undergone enucleation and have orbital implant exposure. Better knowledge regarding the pathogenesis and extracorneal complications of this challen...Continue Reading

Citations

May 28, 2020·Pathogens·Hany M ElsheikhaNaveed Ahmed Khan
Sep 15, 2020·Ophthalmic Plastic and Reconstructive Surgery·Komal AgarwalMohammad Javed Ali
Sep 5, 2020·Case Reports in Ophthalmology·Sophie BataillieHeleen Delbeke

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Methods Mentioned

BETA
confocal microscopy
biopsy
biopsies

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