Orbital metastasis as the presenting symptom of extensive stage small cell lung cancer

European Journal of Internal Medicine
Michelle HenningNava Siegelmann-Danieli

Abstract

Detailed herein are two cases of small cell lung cancer first presenting with orbital metastasis. Orbital metastasis from solid tumors is a rare entity. The predominating primaries in Western countries are breast and lung tumors; hepatocellular and gastric malignancies lead in Japanese series. Clinical symptoms and findings reflect the mass effect and the degree of extra-ocular muscle invasion. Treatment is guided by the cancer type and the tumor histology. The prognosis is grim, and with the exception of rare cases secondary to hormone-responsive tumors, the majority of patients succumb to their disease within a year of diagnosis.

References

May 1, 1990·Ophthalmology·R A Goldberg, J Rootman
Jun 1, 1989·The British Journal of Ophthalmology·R F SpaideP G Paglen
May 1, 1997·The British Journal of Ophthalmology·D H CharS Kroll

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