Orbital metastasis from breast carcinoma presenting as neurotrophic keratitis

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Helena Parente SolariMiguel N Burnier

Abstract

This is a case report of an 81-year-old woman with previous breast cancer. The patient presented with a history of unilateral painless red eye and displayed on examination a nodule in the superior orbital rim, proptosis, and neurotrophic keratitis. Clinical and radiographic examinations were followed by biopsy of the orbital mass. Computed tomography displayed an extraconal mass adjacent to the left superior orbital rim extending to the soft tissues. Light microscopy findings suggested the diagnosis of orbital metastatic breast carcinoma that was confirmed by immunohistochemistry. The histopathologic diagnosis was metastatic adenocarcinoma of the breast to the left orbit. This study emphasizes that orbital metastasis must be considered in patients with ocular complaints and neoplastic disease thought to be stable.

References

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Mar 23, 2002·Ophthalmic Plastic and Reconstructive Surgery·Diana ReevesRichard Lash
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Citations

Dec 3, 2009·Radiology·Daniel E MeltzerDeborah R Shatzkes
Apr 26, 2017·Orbit·Margarita Sánchez OrgazAna Boto-de-Los-Bueis
Dec 16, 2018·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M-S HanetM Ladewig
Dec 10, 2020·BMJ Case Reports·Mairre James Sumang GaddiGerardo Dizon Legaspi
Jul 24, 2020·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Vishaal BhambhwaniAsim Ali

Related Concepts

Biopsy
Mammary Neoplasms, Human
Differential Diagnosis
Keratitis
Orbital Neoplasms
Tomography, X-Ray Computerized Axial
Mammary Ductal Carcinoma

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