Orbital solitary fibrous tumor: a clinicopathologic study from a Chinese tertiary hospital with a literature review

Cancer Management and Research
Jianqin ShenHongguang Cui

Abstract

To report the clinical features, imaging manifestations, histopathology, and immunohistochemical features of several cases of orbital solitary fibrous tumors (SFTs) in a Chinese tertiary hospital, and to undertake a literature review of this rare disease. A non-comparative retrospective review of clinical presentations, imaging manifestations, histopathology, and immunohistochemical features as well as the management and disease outcomes of patients with orbital SFT was conducted along with a review of orbital SFT cases in the literature. This study includes two male and two female patients, with an average age of 53 years. Common presentations among these patients included a palpable subcutaneous mass, swelling of the eyelid, proptosis, diplopia, and vision disturbance. Three patients (cases 2-4) underwent imaging scans. All patients had complete surgical excisions and the tissue was subjected to pathological analysis. One patient (Case 4) experienced a recurrence with malignant transformation and received a re-excision surgery and postoperative radiotherapy. All patients remain alive and well after a minimum follow-up of 12 months (range 12-34 months). Despite its rare occurrence, we suggest that the possibility of orbital SF...Continue Reading

Citations

Mar 1, 2019·Medicine·Ru ZhaoSuisheng Zheng
Dec 27, 2019·Ophthalmic Plastic and Reconstructive Surgery·Nathan W BlessingThomas E Johnson
Jun 24, 2019·Diagnostic Pathology·Ancuta-Augustina Gheorghisan-GalateanuCatalina Poiana
Dec 18, 2020·Medicine·Longyang ChengYuxiang Dai
Jun 5, 2020·Ophthalmic Plastic and Reconstructive Surgery·Chad H JacksonGerald J Harris
Jul 3, 2021·Case Reports in Ophthalmological Medicine·Carmen Navarro-PereaSilvia Pérez-Trigo

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BETA
SMA
surgical resection

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