Orbital swelling as a first symptom in breast carcinoma diagnosis: a case report.

Journal of Medical Case Reports
Elisa FranconeDaniele Friedman

Abstract

The frequency of intra-orbital metastasis in systemic cancer is a controversial topic. Of all metastatic tumors to the orbit of the eye, breast carcinoma is considered to be the most prevalent. Orbital findings typically present themselves after the diagnosis of the primary tumor, with an average delay of three to six years. In spite of that, this study reports a case in which orbital manifestation was the initial symptom in breast carcinoma diagnosis. A 66-year-old Italian Caucasian woman presented with a swelling located on the lower orbit of her right eye. Previous cases report orbital manifestations discovered secondary to breast cancer. This case demonstrates that orbital symptoms may be the primary presentation of the disease. Orbital metastasis originating from breast cancer predicts widespread metastatic disease in other organs. In the presence of an ambiguous infiltrative orbital process, diagnostic examination of the breast is recommended.

References

Jul 1, 1990·Survey of Ophthalmology·R A GoldbergR A Cline
Jan 1, 1994·Virchows Archiv : an International Journal of Pathology·H P SinnI J Diel
Oct 20, 2001·Ophthalmic Plastic and Reconstructive Surgery·J A ShieldsR C Eagle
May 22, 2003·Orbit·Detlef HollandStephan Behrendt
Nov 11, 2008·Japanese Journal of Ophthalmology·Dario SuraceStefano Licci
Nov 27, 2008·Ophthalmic Plastic and Reconstructive Surgery·Tatyana MilmanPaul D Langer

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Citations

Apr 27, 2013·Aesthetic Plastic Surgery·Elisa FranconeDaniele Friedman
Sep 12, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Wendy M ChiangJohn Scott Nystrom
Jun 13, 2018·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Adam KluskaLeszek Gottwald
Oct 24, 2019·Breast Disease·Ismini Michail TsagkarakiElias Alexandros Kotteas

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Methods Mentioned

BETA
biopsy
nuclear magnetic resonance

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