Orbital T-cell lymphoma in youngest recorded patient - early diagnosis, management, and successful outcome: a case report and review of the literature

Journal of Medical Case Reports
Hind Manaa AlkatanYasser H Al-Faky

Abstract

Primary orbital peripheral T-cell lymphoma, not otherwise specified is an exceedingly rare disorder with a very poor outcome, and to the best of our knowledge only a few cases have been reported in the English literature. We present the youngest reported case describing the successful outcome after management with a thorough review of the English literature of all the reported cases of primary peripheral T-cell lymphoma, not otherwise specified. Our patient is a 3-year-old Syrian boy who presented with gradual progressive orbital swelling. A physical examination showed a left orbital dystopia and a superior medial displacement of the globe. Extraocular motility was limited in upward elevation of his left eye. A computed tomography scan and magnetic resonance imaging of his orbit showed a mass involving the lateral and inferior walls of his left orbit and extending intraconally. A diagnosis of peripheral T-cell lymphoma, not otherwise specified was made by careful histopathological examination and Berlin-Frankfurt-Munster protocol was initiated. A 6-month follow up with orbital magnetic resonance imaging showed no sign of orbital or brain involvement. Through this report we emphasize two takeaway lessons: (1) always have a high ...Continue Reading

References

Jan 1, 1972·Cancer·C FreemanS J Cutler
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Sep 29, 2006·Korean Journal of Ophthalmology : KJO·Dong Sub LeeHae Ran Chang
Sep 12, 2007·Archives of Ophthalmology·Kim A JanatpourWilliam C Lloyd
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Aug 12, 2009·Archives of Ophthalmology·Ying-Jen ChenMing-Cheng Tai
Jan 29, 2011·Blood·Dennis D WeisenburgerUNKNOWN International Peripheral T-cell Lymphoma Project
Oct 23, 2012·BMJ Case Reports·Sonal AmitShrivastava Kanchan
Oct 25, 2013·BMJ Case Reports·Joel J GagnierUNKNOWN CARE Group
Sep 1, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F d'AmoreUNKNOWN ESMO Guidelines Committee

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Methods Mentioned

BETA
biopsy
electrophoresis
PCR

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