Orchestrating the orchestrators: chemokines in control of T cell traffic.

Nature Immunology
Shannon K BromleyAndrew D Luster

Abstract

The understanding of how chemokines orchestrate the trafficking and activity of immune cells has increased considerably. So far, over 50 chemokines and 20 chemokine receptors have been identified. Detailed analyses have demonstrated the function of chemokine receptors on T cell subsets, the temporal and spatial expression patterns of chemokines in vivo and the phenotypes of animals genetically deficient in one component or several components of the chemokine-chemokine receptor system. New microscopy modalities for studying the influence of chemokines on the migratory activity of T cells in the lymph node have also brought new insights. Here we review such advances with particular emphasis on control of the migration of T cell subsets in lymph nodes and in peripheral tissues in homeostasis and inflammation.

References

Sep 1, 1992·European Journal of Immunology·C R MackayL Dudler
Jan 1, 1997·Annual Review of Immunology·A BendelacJ H Roark
Oct 19, 1999·The Journal of Experimental Medicine·G VassilevaS A Lira
Feb 10, 2000·Springer Seminars in Immunopathology·U SyrbeA Hamann
Nov 9, 2000·Proceedings of the National Academy of Sciences of the United States of America·S A LutherJ G Cyster
Dec 20, 2000·The Journal of Clinical Investigation·N A KuklinH B Greenberg
Dec 21, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·D P AndrewL Wu
May 9, 2001·The Journal of Experimental Medicine·E S BaekkevoldG Haraldsen
Jul 4, 2001·The Journal of Experimental Medicine·D C HargreavesJ G Cyster
Apr 26, 2002·Current Opinion in Immunology·Jane L Grogan, Richard M Locksley
May 8, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Andrea GlatzelDieter Kabelitz
Jun 22, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sanjiv A LutherJason G Cyster
Jul 3, 2002·The Journal of Experimental Medicine·Takaharu OkadaJason G Cyster
Aug 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Veronika SzanyaC Garrison Fathman
Jan 16, 2003·Immunology Letters·Allan Randrup ThomsenJan Pravsgaard Christensen
Aug 6, 2003·Current Opinion in Immunology·Michael D CahalanMark J Miller
Aug 21, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Seddon Y ThomasAndrew D Luster
Sep 2, 2003·Nature Immunology·Andrew M TagerAndrew D Luster
Sep 10, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Brent JohnstonEugene C Butcher
Sep 23, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mark S SundrudDerya Unutmaz
Dec 12, 2003·Nature Reviews. Immunology·Ulrich H von Andrian, Thorsten R Mempel
Mar 23, 2004·Annual Review of Immunology·Antal Rot, Ulrich H von Andrian
Apr 21, 2004·The Journal of Experimental Medicine·M Lucila ScimoneWolfgang Weninger
May 4, 2004·Nature Reviews. Immunology·Klaus Ley, Geoffrey S Kansas
Aug 5, 2004·Blood·Christoph HessAndrew D Luster
Apr 6, 2005·The Journal of Experimental Medicine·Iris LeeWayne W Hancock
Jun 10, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Timothy L DenningMitchell Kronenberg
Jul 15, 2005·Blood·Graham M LordLaurie H Glimcher

❮ Previous
Next ❯

Citations

Oct 12, 2013·Biogerontology·Adi Sagiv, Valery Krizhanovsky
Jan 29, 2010·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Mohamed El-behiBogoljub Ciric
Feb 3, 2009·Immunologic Research·Dorothy K SojkaDeborah J Fowell
Aug 21, 2009·Expert Reviews in Molecular Medicine·James A Deane, Michael J Hickey
Dec 14, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Michael T BesteDaniel A Hammer
Feb 14, 2013·Journal of Proteome Research·Ruibing ChenNing Zhang
May 11, 2011·Immunology and Cell Biology·Charlotte F InmanStephen Cose
Jan 11, 2011·Nature Immunology·Sabina A IslamAndrew D Luster
Apr 2, 2013·Nature Immunology·Jason M SchenkelDavid Masopust
Aug 20, 2008·Nature Immunology·Peter Friedl, Bettina Weigelin
May 9, 2012·Nature Medicine·Sabina A Islam, Andrew D Luster
Apr 7, 2010·Proceedings of the National Academy of Sciences of the United States of America·Xiaodong JiangThomas S Kupper
Jan 12, 2011·Proceedings of the National Academy of Sciences of the United States of America·Boris CalderonEmil R Unanue
Jun 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Christina M BakerMinsoo Kim
Mar 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Graeme O'BoyleJohn A Kirby
Feb 16, 2012·The Journal of Biological Chemistry·Luigi RacioppiAnthony R Means
Oct 17, 2012·The Journal of Biological Chemistry·Prabha ChandrasekaranSundararajan Venkatesan
Jul 27, 2011·The Journal of Experimental Medicine·Jacob E KohlmeierDavid L Woodland
Mar 12, 2013·Antioxidants & Redox Signaling·Djordje Miljković, Ivan Spasojević
Jul 28, 2012·International Immunology·Simone H C HavenithIneke J M ten Berge
Jul 18, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Holger HägeleHans-Joachim Anders
Feb 15, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Lee FaulknerB Kevin Park
Oct 16, 2010·Journal of Immunotherapy·Lynn T DengelDavid W Mullins
May 21, 2009·AIDS·Santiago Perez-PatrigeonLisa A Chakrabarti
Mar 29, 2011·Transplantation·Denise J LoAllan D Kirk
May 31, 2012·Open Biology·Selvakumar SubbianGilla Kaplan
Mar 3, 2010·Infection and Immunity·Shahani NoorEmma H Wilson
Jul 22, 2011·Journal of Virology·Jarad J WilsonAron E Lukacher
Jul 10, 2010·Journal of Biomedicine & Biotechnology·Hiroshi OkamotoHisashi Yamanaka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.