Orf virus infection in Alaskan mountain goats, Dall's sheep, muskoxen, caribou and Sitka black-tailed deer

Acta Veterinaria Scandinavica
Morten TrylandJoern Klein

Abstract

The zoonotic Orf virus (ORFV; genus Parapoxvirus, Poxviridae family) occurs worldwide and is transmitted between sheep and goats, wildlife and man. Archived tissue samples from 16 Alaskan wildlife cases, representing mountain goat (Oreamnos americanus, n = 8), Dall's sheep (Ovis dalli dalli, n = 3), muskox (Ovibos moschatus, n = 3), Sitka black-tailed deer (Odocoileus hemionus sitkensis, n = 1) and caribou (Rangifer tarandus granti, n = 1), were analyzed. Clinical signs and pathology were most severe in mountain goats, affecting most mucocutaneous regions, including palpebrae, nares, lips, anus, prepuce or vulva, as well as coronary bands. The proliferative masses were solid and nodular, covered by dark friable crusts. For Dall's sheep lambs and juveniles, the gross lesions were similar to those of mountain goats, but not as extensive. The muskoxen displayed ulcerative lesions on the legs. The caribou had two ulcerative lesions on the upper lip, as well as lesions on the distal part of the legs, around the main and dew claws. A large hairless spherical mass, with the characteristics of a fibroma, was sampled from a Sitka black-tailed deer, which did not show proliferative lesions typical of an ORFV infection. Polymerase chain r...Continue Reading

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Citations

May 20, 2020·Frontiers in Veterinary Science·Laura GallinaAlessandra Scagliarini
May 22, 2021·Animal Health Research Reviews·Zaharaddeen LawanMohd Lila Mohd-Azmi
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Elise M RingwaldtJessie C Buettel
Jul 3, 2021·International Journal of Environmental Research and Public Health·Javier Sánchez RomanoAnn Albihn
Sep 21, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Ignacio Morales-CastillaT Jonathan Davies

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Datasets Mentioned

BETA
AY386264.1
HM133903.1
DQ184476.1
KP010354.1
KF234407.1

Methods Mentioned

BETA
PCR
electrophoresis
PCRs

Software Mentioned

Primer
LAGAN
BLAST
BioNJ

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