Organ failure, aetiology and 7-day all-cause mortality among acute adult patients on arrival to an emergency department: a hospital-based cohort study.

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
Peter Bank PedersenAnnmarie Touborg Lassen

Abstract

Organ failure is both a frequent and dangerous condition among adult patients on arrival to an emergency department (ED). The risk of an unfavourable outcome could depend on the underlying aetiology. Knowledge of the relation between aetiology and prognosis could improve the risk stratification at arrival. To describe the relation between organ failure, aetiology and prognosis through 7-day all-cause mortality. An observational three-year cohort study at the ED at Odense University Hospital, Denmark, including all acute adult patients.First-measured vital signs and laboratory values were included to evaluate the presence of the following organ failures: respiratory, coagulation, hepatic, circulatory, cerebral or renal.The primary outcome was 7-day all-cause mortality. Aetiological disease categories were based on primary discharge diagnoses. We described the association between 7-day mortality, aetiology category, site of organ failures and number of patients at risk. Of 40 423 patients with a first-time visit at the ED, 5883(14.6%) had an organ failure on arrival. The median age was 69 (IQR 54-80), and 50% were men. The most frequent aetiology was infection (1495, 25.4%). Seven-day all-cause mortality ranged between aetiologie...Continue Reading

References

Sep 29, 2009·Journal of Critical Care·Wendy LimDeborah Cook
Nov 23, 2012·Critical Care : the Official Journal of the Critical Care Forum·Jean-Louis VincentJan Bakker
Oct 2, 2013·Mayo Clinic Proceedings·Lars W AndersenMichael W Donnino
Oct 4, 2013·The Journal of Trauma and Acute Care Surgery·Matthew BennsCarrie A Sims
Jun 27, 2014·European Journal of Epidemiology·Morten SchmidtHenrik Toft Sørensen
Mar 11, 2015·Emergency Medicine Journal : EMJ·Mathilde PedersenAnnmarie Touborg Lassen
Jul 15, 2015·American Journal of Respiratory and Critical Care Medicine·Matthew M ChurpekDana P Edelson
Nov 12, 2015·Intensive Care Medicine·Sebastian A HaasStefan Kluge
Nov 26, 2015·Clinical Epidemiology·Morten SchmidtHenrik Toft Sørensen
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Christopher W SeymourDerek C Angus
Dec 17, 2016·Shock·Jon Gitz HollerAnnmarie Touborg Lassen
Jan 24, 2018·Surgical Infections·Markus T Ziesmann, John C Marshall
Feb 13, 2018·Critical Care Medicine·Alejandro SchulerVincent X Liu
Apr 25, 2018·Nature Reviews. Nephrology·Christophe Lelubre, Jean-Louis Vincent
Aug 1, 2019·Journal of Clinical Medicine·Lisa MellhammarFredrik Kahn

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