Apr 1, 1976

Organic anions induce colinic secretion

The American Journal of Digestive Diseases
L Bustos-FernándezK O de Furuya

Abstract

Experiments were conducted by instilling test solutions into the cleaned colon of anesthetized rats. Isotonic test solutions at an acid (2.9% or neutral (7.0) pH and containing acetic acid or acetate ions were used. At the lower pH, acetic acid was absorbed well absorbed and the colon absorbed fluid. The secretory effect could not be reproduced by hydrochloric acid solutions at pH 2.9. Fluid secretion induced by acetic acid was associated with discharge of mucus from goblet cells. The interference of colonic absorption by acetic acid might be important in some diarrheal diseases.

  • References17
  • Citations6

References

  • References17
  • Citations6

Citations

Mentioned in this Paper

Taenia Coli
Potassium
Process of Secretion
Structure of Intestinal Gland
Sodium
Colon Structure (Body Structure)
Cell Secretion
Mucous Body Substance
Dysentery
Water-Electrolyte Balance

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