Organic UV filter exposure and pubertal development: A prospective follow-up study of urban Chinese adolescents

Environment International
Yanran HuangKelvin Sze-Yin Leung

Abstract

UV filters, widely used in personal care and industrial products, are being found in the environment and, in humans where with limited understanding on their potential health effects, especially during puberty. To examine the association between UV filter exposure and pubertal development in a prospective follow-up study. This study included 521 elementary and high school students from a suburban area of Shanghai. The initial study was done in October to November 2011; the follow-up study in April to May 2013. Twelve urinary organic UV filters were quantified, and the pubertal development was assessed at each study period by trained physicians using Tanner staging. We used (ordered) logistic regression model and multilevel mixed-effect (ordered) logistic regression model to assess cross-sectional and longitudinal effects between urinary concentration of five major UV filters and pubertal development of stages, onset and pace. Ethylhexyl methoxycinnamate (EHMC) and its metabolite 4'-methoxyacetophenone (4'-MAP), two benzophenone derivatives (BP-2, BP-3) and Ethylhexyl dimethyl PABA (OD-PABA) were the most extensively detected UV filters in urine with geometric means (95% CI) in 2010 and 2012 as 1.77 (1.599, 1.956) and 2.28 (1.98...Continue Reading

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Citations

May 15, 2021·Journal of Environmental Sciences (China)·Peng ZhangRanran Zhou
May 16, 2021·Integrated Environmental Assessment and Management·Bareum Kwon, Kyungho Choi

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