PMID: 9552423Jan 1, 1997Paper

Organisation and functional regulation of the centrosome in animal cells

Progress in Cell Cycle Research
A Paoletti, M Bornens

Abstract

Molecular characterisation of centrosomal components is slowly progressing. Recent results indicate that the major aspects of centrosome-mediated microtubule nucleation may soon be understood at the molecular level. In contrast, centrosome reproduction, which is an important aspect of animal cell division, remains terra incognita. The most challenging issue for the future is to understand the molecular mechanisms which control centrosome biogenesis. There is a urgent need to identify with certainty proteins implicated in this process. Comparison between organisms with structurally different centrosomes might be critical for a better understanding of centrosome duplication if a general mechanism has been conserved throughout evolution.

Citations

Aug 28, 2003·Médecine sciences : M/S·Régis Giet, Claude Prigent
Jun 8, 2000·Microscopy Research and Technique·C Zeng
Mar 20, 2010·Cellular and Molecular Life Sciences : CMLS·Alain DebecMonica Bettencourt-Dias
May 21, 2013·Eukaryotic Cell·Jessica Cruz de LeonNaomi S Morrissette
Dec 13, 2005·Biochemistry. Biokhimii︠a︡·J V Tkemaladze, K N Chichinadze
Apr 25, 2000·European Journal of Cell Biology·J De RyckeC Tasca

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