PMID: 1203044Sep 1, 1975Paper

Organization of experimental thrombi in arteries and veins. A comparative study (author's transl)

Basic Research in Cardiology
H Frenzel, W Hort

Abstract

Thrombi were produced in 62 female white rats (Sprague-Dawley) by injection of thrombin in the right common carotid artery and in the left vena iugularis as well. Partly the vessels were ligatured proximal and distal of the thrombus, partly they were closed with one ligature. In this latter group (one ligature) the thrombus was exposed to the blood-pressure, while in the first group the thrombus was protected against the blood-waves. After 2, 4, 6, 8, 10 and 14 days as after 4 and 6 weeks the rats were sacrificed and the thrombosed vessel-segments were studied by light-microscope. In the arterie we found occlusive thrombi. In the veins the thrombi were higher in fibrin content than in the arteries. Between the thrombus and the endothelium of the vein-wall there was a sinus which became wider with aging of the thrombus. In the first days the progression of thrombus-organization was more rapid in veins than in arteries; endothelial cells, fibroblasts and capillary buds invaded the thrombus more extensive. In veins there was no difference in composition and organization of the thrombi of the two groups. In the thrombosed veins often small capillaries could be seen running through the vessel wall into the tissue of the organized th...Continue Reading

References

Dec 1, 1965·Circulation Research·H C Kwaan, T Astrup
Feb 1, 1967·The Australian and New Zealand Journal of Surgery·J S Cox
Apr 1, 1969·The Journal of Pathology·M J DaviesJ P Bradley
Mar 1, 1971·The British Journal of Surgery·A M Karmody, F Walker
Jul 1, 1968·The British Journal of Surgery·C Flanc
Apr 1, 1953·The Journal of Pathology and Bacteriology·R M MEHROTRA
Jan 1, 1955·The Journal of Pathology and Bacteriology·G WILLIAMS
Jul 1, 1958·The Journal of Pathology and Bacteriology·I FILSHIE, G B SCOTT
Jul 1, 1959·The Journal of Pathology and Bacteriology·A S TODD
Dec 1, 1962·Angiology·R L HENRY
Jan 1, 1950·The Journal of Pathology and Bacteriology·Y Y AKRAWI, G M WILSON

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Citations

Jan 1, 1980·Virchows Archiv. A, Pathological Anatomy and Histology·H FrenzelW Hort

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