Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography

Neuroscience
H J Groenewegen

Abstract

The aim of the present study was to determine the organization of the afferents of the mediodorsal thalamic nucleus in relation to the reciprocal connections of this nucleus with different areas of the prefrontal cortex. For this purpose injections of horseradish peroxidase, or horseradish peroxidase conjugated to wheatgerm agglutinin were placed in different parts of the mediodorsal nucleus. These experiments revealed the organization of the reciprocal mediodorsal-prefrontal connections since wheatgerm agglutinin-horseradish peroxidase is transported effectively in anterograde and retrograde directions. Injections of wheatgerm agglutinin-horseradish peroxidase or fluorescent tracers were placed in different portions of the prefrontal cortex, and the lectin Phaseolus vulgaris leucoagglutinin was injected in the mediodorsal nucleus in order to verify in more detail the point-to-point relationship in the mediodorsal-prefrontal connections. The organization of a number of the subcortical afferents to the mediodorsal nucleus was determined in detail using injections of Phaseolus vulgaris leucoagglutinin, wheatgerm agglutinin-horseradish peroxidase, or tritiated amino acids in areas identified as a source of mediodorsal afferents in...Continue Reading

References

Feb 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Feb 15, 1976·The Journal of Comparative Neurology·M B CarpenterR Kim
Jan 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Feb 15, 1979·The Journal of Comparative Neurology·C B SaperW M Cowan
Sep 1, 1979·The Journal of Comparative Neurology·M Herkenham, W J Nauta
Oct 1, 1979·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
Sep 28, 1977·Experimental Brain Research·J Kievit, H G Kuypers
Feb 1, 1979·The Journal of Comparative Neurology·M Herkenham
May 15, 1976·The Journal of Comparative Neurology·L W Swanson
Apr 1, 1975·The Journal of Comparative Neurology·L A Benevento, J H Fallon
Nov 15, 1985·The Journal of Comparative Neurology·C G van Eden, H B Uylings
Dec 22, 1985·The Journal of Comparative Neurology·P S Goldman-Rakic, L J Porrino
Jul 1, 1986·The Journal of Comparative Neurology·H J GroenewegenW J Nauta
Sep 22, 1986·The Journal of Comparative Neurology·P Room, H J Groenewegen
Nov 15, 1986·The Journal of Comparative Neurology·K Satoh, H C Fibiger
Jul 15, 1985·The Journal of Comparative Neurology·R A McCrea, R Baker
Jan 22, 1987·The Journal of Comparative Neurology·D S ZahmL Heimer
Mar 15, 1987·The Journal of Comparative Neurology·A I LeveyB H Wainer
Aug 6, 1986·Brain Research·E KosarR Norgren
Jan 15, 1985·The Journal of Comparative Neurology·T Takahashi
Mar 11, 1985·Brain Research·F T RusschenJ L Price
May 15, 1985·The Journal of Comparative Neurology·S N HaberW J Nauta

Citations

Sep 19, 1998·The Journal of Comparative Neurology·C J Shi, M D Cassell
Aug 15, 2001·The Journal of Comparative Neurology·M GotoN S Canteras
Sep 8, 1990·The Journal of Comparative Neurology·H W Berendse, H J Groenewegen
Aug 25, 2007·Brain Structure & Function·Walter B Hoover, Robert P Vertes
Jan 10, 2009·Brain Structure & Function·Margriet J Dolleman-van der WeelM P Witter
Jan 25, 2012·Brain Structure & Function·Judy A PrasadYogita Chudasama
Aug 31, 2012·Brain Structure & Function·Anushree TripathiElisa Mengual
Feb 20, 2007·Journal of Neural Transmission·R Alelú-Paz, J M Giménez-Amaya
Apr 10, 2012·Cellular and Molecular Neurobiology·Matthew W HaleChristopher A Lowry
Mar 1, 1991·Behavioral and Neural Biology·P R Hunt, J P Aggleton
Jul 15, 1994·Brain Research. Developmental Brain Research·C G van EdenH B Uylings
Dec 15, 1994·Behavioural Brain Research·T YamamotoN Sakai
Mar 1, 1995·Neuroscience Research·T YamamotoN Sakai
Aug 1, 1993·Progress in Neurobiology·J D Cooper, O T Phillipson
Nov 20, 1989·Neuroscience Letters·S L BuchananR H Thompson

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.