Organization of the colliculo-suprageniculate pathway in the cat: a wheat germ agglutinin-horseradish peroxidase study

The Journal of Comparative Neurology
Y Katoh, György Benedek

Abstract

A wheat germ-agglutinated horseradish peroxidase (WGA-HRP) tracing technique was used to label the cell bodies of neurons in the superior colliculus that send projections into the visually sensitive region of the suprageniculate nucleus (Sg) in the feline thalamus. After determination of the position of the Sg by detecting characteristic single-unit responses to moving visual stimuli, WGA-HRP was injected into the Sg in five pentobarbital-anesthetized cats. The animals were than sacrificed, and serial frozen sections of the midbrain were processed for the demonstration of peroxidase activity. A total of 2,736 WGA-HRP-stained neurons were located within the ipsilateral superior colliculus (SC), and a few labeled cells were consistently found bilaterally in the external nuclei of the inferior colliculus. In each cat, a small but significant fraction of the labeled cells were encountered contralateral to the injection. Medial SC neurons tended to project to the posterior Sg, and lateral SC neurons tended to project to more rostral Sg. However, labeled cells were distributed homogeneously along the rostrocaudal extent of the SC, indicating the absence of a well defined topographic relationship. Nor was the Sg injection site locatio...Continue Reading

References

Feb 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Dec 1, 1978·The Journal of Comparative Neurology·D L Oliver, W C Hall
Mar 1, 1975·Experimental Neurology·L A Benvento, P R Loe
Oct 1, 1979·Journal of Neuroscience Methods·M Armstrong-James, J Millar
Jan 18, 1978·Experimental Brain Research·R Mason
Mar 21, 1975·Brain Research·D L Oliver, W C Hall
Apr 1, 1975·The Journal of Comparative Neurology·L A Benevento, J H Fallon
Mar 1, 1976·Journal of Neurophysiology·B E SteinL Kruger
Apr 22, 1986·The Journal of Comparative Neurology·T P HicksW A Fletcher
May 15, 1988·The Journal of Comparative Neurology·B P Abramson, L M Chalupa
Jul 15, 1989·The Journal of Comparative Neurology·B Hutchins, B V Updyke
Aug 1, 1988·Journal of Neurophysiology·T P HicksG A Thurlow
Jan 1, 1986·Experimental Brain Research·M NoritaO D Creutzfeldt
Jul 23, 1986·Brain Research·D S YamasakiR W Rhoades
Apr 1, 1971·The Journal of Comparative Neurology·C J Heath, E G Jones
Mar 1, 1973·Electroencephalography and Clinical Neurophysiology·C C Huang, D B Lindsley
Jul 1, 1974·The Journal of Comparative Neurology·V A Casagrande, I T Diamond
Dec 1, 1974·The Journal of Comparative Neurology·T Kanaseki, J M Sprague
Jul 1, 1972·Experimental Neurology·B E Stein, M O Arigbede
Mar 1, 1973·Journal of Neurophysiology·B Gordon
Jan 1, 1970·Experimental Brain Research·M Straschill, K P Hoffmann

❮ Previous
Next ❯

Citations

Oct 10, 1998·The Journal of Comparative Neurology·T A HackettJ H Kaas
Apr 14, 2007·Experimental Brain Research·Wioletta J WaleszczykGyörgy Benedek
Aug 10, 2002·The European Journal of Neuroscience·José Carlos DávilaSalvador Guirado
Jan 1, 2010·Sensors·Alice RokszinAttila Nagy
Aug 6, 2003·The Journal of Comparative Neurology·Larry R KellyMartha E Bickford
Nov 18, 2006·The Journal of Comparative Neurology·Khaleel A RazakZoltan M Fuzessery
Apr 21, 2007·The Journal of Comparative Neurology·Troy A HackettCharles E Schroeder
Jul 24, 2010·The Journal of Comparative Neurology·Philip H SmithDaniel J Uhlrich
May 5, 2009·The Journal of Comparative Neurology·Khaleel A RazakZoltan M Fuzessery
Jun 13, 2020·Current Biology : CB·Hyoung F KimOkihide Hikosaka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.