Organization of the human inferior parietal lobule based on receptor architectonics

Cerebral Cortex
Svenja CaspersKarl Zilles

Abstract

Human inferior parietal lobule (IPL) plays a key role in various cognitive functions. Its functional diversity, including attention, language, and action processing, is reflected by its structural segregation into 7 cytoarchitectonically distinct areas, each with characteristic connectivity patterns. We hypothesized that commonalities of the cytoarchitectonic, connectional, and functional diversity of the IPL should be reflected by a correlated transmitter receptor-based organization. Since the function of a cortical area requires a well-tuned receptor balance, the densities of 15 different receptors were measured in each IPL area. A hierarchical cluster analysis of the receptor balance revealed a tripartite segregation of the IPL into a rostral, middle, and caudal group. Comparison with other cortical areas showed strong similarities with Broca's region for all 3 groups, with the superior parietal cortex for the middle, and with extrastriate visual areas for the caudal group. Notably, caudal-most area PGp has a receptor fingerprint very similar to that of ventral extrastriate visual cortex. We therefore propose a new organizational model of the human IPL, consisting of 3 clusters, which corresponds to its known cytoarchitecton...Continue Reading

References

Jan 1, 1992·Trends in Neurosciences·M A Goodale, A D Milner
Nov 1, 1983·Journal of Neuroscience Methods·B Merker
Jan 10, 1982·The Journal of Comparative Neurology·D N Pandya, B Seltzer
Jan 1, 1984·Experimental Brain Research·B Seltzer, D N Pandya
Jul 1, 1982·Physiological Reviews·J Hyvärinen
Sep 1, 1995·Neuropsychologia·A D Milner
Jan 1, 1995·International Journal of Technology Assessment in Health Care·M Milner
Apr 1, 1994·Current Opinion in Neurobiology·L G Ungerleider, J V Haxby
Aug 29, 1996·Nature·S GeyerP E Roland
Jul 11, 1998·The Journal of Comparative Neurology·S GeyerK Zilles
Jul 1, 1999·NeuroImage·S GeyerK Zilles
Aug 12, 1999·The Journal of Comparative Neurology·K AmuntsK Zilles
Aug 26, 1999·Neuropharmacology·N M Barnes, T Sharp
Mar 17, 2000·Brain Research. Brain Research Reviews·P S Goldman-RakicG V Williams
Nov 1, 2000·International Journal of STD & AIDS·G D Barlow, A J France
May 25, 2001·NeuroImage·K Zilles, N Palomero-Gallagher
Jul 5, 2001·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·M F RushworthP K Sipila
Mar 5, 2002·Nature Immunology
May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
Sep 18, 2002·Progress in Neurobiology·Marie E Gibbs, Roger J Summers
Dec 7, 2002·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·K ZillesA Schleicher
Sep 12, 2003·Trends in Pharmacological Sciences·Clare BergsonMichael S Lidow
Oct 15, 2003·Neuron·David S Bredt, Roger A Nicoll
Apr 15, 2004·Immunology Letters·Thomas Wossning, Michael Reth
Apr 30, 2004·CNS Spectrums·Joseph I FriedmanJack M Gorman
Oct 12, 2004·Neuron·Joshua D GreeneJonathan D Cohen
Dec 22, 2004·Journal of Anatomy·Karl ZillesAxel Schleicher
Apr 30, 2005·Science·Leonardo FogassiGiacomo Rizzolatti
May 18, 2005·Psychiatric Rehabilitation Journal·Kam-Shing Yip
May 21, 2005·Clinical Psychology Review·Christopher G Beevers
Sep 13, 2005·Waste Management·Kai FreudenthalJoachim Behrendt
Sep 20, 2005·Anatomy and Embryology·P MorosanK Zilles
Sep 30, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Paula L CroxsonMatthew F S Rushworth
Oct 14, 2005·Anatomy and Embryology·Giacomo Rizzolatti
Oct 27, 2005·Anatomy and Embryology·A SchleicherK Zilles
Nov 8, 2005·Current Opinion in Neurobiology·Marco Iacoboni

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Citations

Feb 1, 2014·Brain : a Journal of Neurology·Jennifer G GoldmanChristopher G Goetz
Jun 27, 2015·Neuroscience and Biobehavioral Reviews·Roberto CaminitiAlexandra Battaglia-Mayer
Mar 5, 2016·Brain Structure & Function·Christiane JockwitzKarl Zilles
Mar 26, 2016·Frontiers in Integrative Neuroscience·Yuki Murai, Yuko Yotsumoto
Oct 24, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Talia HermanJeffrey M Hausdorff
Oct 11, 2015·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Avinash RamyeadAnita Riecher-Rössler
Jan 17, 2015·Neuropsychologia·Anna Leshinskaya, Alfonso Caramazza
Sep 5, 2015·Brain Structure & Function·Pascale Tremblay, Isabelle Deschamps
Sep 4, 2015·Reading and Writing·Virginia W BerningerRobert D Abbott
Nov 19, 2013·Cerebral Cortex·Lukas HenselSimon B Eickhoff
Sep 23, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Karl ZillesAngela D Friederici
Sep 29, 2012·Cerebral Cortex·J Benjamin HutchinsonAnthony D Wagner
Jun 7, 2014·Frontiers in Human Neuroscience·Fabio Richlan
Apr 29, 2016·Nature·Alexander G HuthJack L Gallant
May 22, 2016·Human Brain Mapping·Martijn P van den HeuvelLisa Feldman Barrett
Oct 31, 2016·Neuroscience·Alexandra Battaglia-MayerEleonora Satta
Mar 20, 2013·NeuroImage·Christopher BaldassanoLi Fei-Fei
Aug 23, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Emma Jane RoseElliot A Stein
Jan 22, 2017·Neuroscience and Biobehavioral Reviews·Elena BorraGiuseppe Luppino
Jan 28, 2017·AJNR. American Journal of Neuroradiology·L M AlhilaliS Fakhran
Mar 3, 2017·Scandinavian Journal of Psychology·Linda WendelbergSule Yildirim-Yayilgan
May 16, 2017·The European Journal of Neuroscience·Johannes BrandKynan Eng

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