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Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex

Chemistry & Biology

Dec 4, 2003

Shi ChenZixin Deng

PMID: 14652074

Abstract

The complete gene cluster for biosynthesis of a polyene complex, FR-008, spans 137.2 kb of the genome of Streptomyces sp. FR-008 consisting of six genes for a modular PKS and 15 additional genes. The extensive similarity to the partially characterized candicidin gene cluster in Streptom...read more

Mentioned in this Paper

Genes, Reiterated
Gene Deletion Abnormality
Homologous Sequences, Amino Acid
Aminotransferase Activity
Genes, Regulator
Polyenes
mycosamine
Oligonucleotide Primers
Deletion Mutation
Transaminases
Paper Details
References
  • References27
  • Citations52
123
  • References27
  • Citations52
12345...

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Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex

Chemistry & Biology

Dec 4, 2003

Shi ChenZixin Deng

PMID: 14652074

DOI:

Abstract

The complete gene cluster for biosynthesis of a polyene complex, FR-008, spans 137.2 kb of the genome of Streptomyces sp. FR-008 consisting of six genes for a modular PKS and 15 additional genes. The extensive similarity to the partially characterized candicidin gene cluster in Streptom...read more

Mentioned in this Paper

Genes, Reiterated
Gene Deletion Abnormality
Homologous Sequences, Amino Acid
Aminotransferase Activity
Genes, Regulator
Polyenes
mycosamine
Oligonucleotide Primers
Deletion Mutation
Transaminases

Similar Papers Found In These Feeds

Glycolipids

Glycolipids are amphitropic compounds with one or more monosaccharide residues glycosidically linked to a lipid. Discover the latest research on glycolipids here.

Chromosomal Deletion

Chromosomal deletion includes the loss of a gene sequence of DNA. The location and the genes deleted determines the significance of this abnormality. There are many identified genetic disorders that are a result from chromosomal deletion including cri du chat and Prader-Willi syndrome. Discover the latest research on chromosomal deletions here.

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Paper Details
References
  • References27
  • Citations52
123
  • References27
  • Citations52
12345...
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