Organizing pneumonia

La Presse médicale
B CrestaniMichel Aubier

Abstract

Organizing pneumonia is first of all a pathologic entity observed in different situations of pulmonary repair after aggression. It is characterized by the presence in the distal airways (alveoli, alveolar ducts, and respiratory bronchioli) of fibroblastic buds in a loose extracellular matrix. The same terminology also describes a clinical entity characterized by the appearance of patches of multiple alveolar opacities, especially suggestive when they are migratory. This entity is characterized by strong sensitivity to corticosteroids and the high frequency of disease relapses, which generally occur when the corticosteroid dose is reduced or in the weeks after treatment stops. Diagnostic certainty requires histologic proof, which is rarely obtained when the radiographic and clinical picture is typical. When it occurs without an identified cause, this entity is now known as cryptogenic organizing pneumonia (it was previously called bronchiolitis obliterans with organizing pneumonia, or BOOP). The same entity can be observed in other defined contexts (connective tissue disease, for example), or with identified causes (e.g., radiation therapy for breast cancer, drugs, or infections).

References

Jul 11, 1992·Chest·T E King, R L Mortenson
Jan 17, 1985·The New England Journal of Medicine·G R EplerE A Gaensler
Apr 22, 2003·AJR. American Journal of Roentgenology·Sang Jin KimKi Jun Sung
May 13, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jo Ann LindenfeldRonald Zolty
Apr 6, 2006·Annals of Internal Medicine·Laure ChampionEmmanuel Morelon
Aug 2, 2006·The European Respiratory Journal·J-F Cordier

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Citations

Sep 3, 2011·La Presse médicale·Alban DerouxChristian Massot
Dec 8, 2009·La Presse médicale·Marc Humbert
Nov 30, 2011·Revue des maladies respiratoires·A Ibn SellamK Alaoui-Tahiri
Jul 30, 2010·Wiener klinische Wochenschrift·Katja SchindlerJosef F Kaliman
May 24, 2021·Respiratory Medicine and Research·C Rolland-DebordJ Cadranel

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