PMID: 2505400Jul 1, 1989Paper

Origin and behaviour of emphysematous bullae

Thorax
M D MorganH R Matthews

Abstract

Giant emphysematous bullae are believed to produce symptoms of pulmonary compression and collapse by containing gas under pressure that has been generated through valvular feeding airways. To examine this hypothesis, we have measured oxygen and carbon dioxide tensions (PO2, PCO2) in four patients and pressure within the bullae in three patients immediately before surgery. During spontaneous tidal respiration PO2 in the bulla was higher than arterial PO2 but did not rise as fast during the breathing of oxygen. The intra-bulla pressure during inspiration was negative (-5.5 to -19 cm H2O) and similar to pleural pressure in phase and degree. During intermittent positive pressure ventilation in two patients airway pressures were transmitted to the bulla with the development of a positive end expiratory pressure within the bulla. Histological examination of the walls of the bullae in the four patients and adjacent lung tissue in an additional patient failed to identify any valvular mechanism. The available information suggests that bullae develop after retraction and collapse of surrounding lung away from a region of weakness.

References

Mar 10, 1978·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·T Takishima
Jan 1, 1987·Journal of Applied Physiology·A BaydurC S Sassoon
Feb 1, 1983·Thorax·M G Pearson, C Ogilvie
Jan 1, 1984·Clinical Radiology·D H Carr, N B Pride
Jan 1, 1984·British Journal of Diseases of the Chest·M D Morgan, B Strickland
Apr 1, 1983·Chest·P K BehrakisJ Milic-Emili
Feb 1, 1982·Journal of Computer Assisted Tomography·D FioreF Calabró
Dec 1, 1981·Thorax·P D PotgieterA D Ferguson
Apr 1, 1963·The American Review of Respiratory Disease·E Y TINGH A LYONS

❮ Previous
Next ❯

Citations

May 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P D Slinger
Aug 9, 2013·Lung·Christian GhattasDavid J Gemmel
Jul 14, 2011·JAAPA : Official Journal of the American Academy of Physician Assistants·Amy L Jay
Jan 27, 1990·BMJ : British Medical Journal·W J Kinnear, A E Tattersfield
Aug 1, 1991·Thorax·U U NkereS W Fountain
May 1, 1996·Thorax·D A BradshawD E Amundson
Oct 5, 2010·Indian Journal of Anaesthesia·S Parthasarathy, M Ravishankar
Nov 21, 1998·Chest·M A Judson, C Strange
Oct 24, 2012·Anesthesiology Clinics·Peter Slinger, Bruce Kilpatrick
May 23, 2008·Best Practice & Research. Clinical Anaesthesiology·Peter Slinger
Sep 1, 2004·The Annals of Thoracic Surgery·Paul H SchipperJoel D Cooper
Feb 18, 1998·Radiologic Clinics of North America·J E Takasugi, J D Godwin
Sep 9, 2015·Case Reports in Pulmonology·Erdoğan ÇetinkayaMustafa Çörtük
Feb 18, 2005·Respiratory Medicine·Marco MuraMario Fabbri
May 1, 1995·Respiratory Medicine·Z K Wahbi, A G Arnold
Sep 1, 1991·The Annals of Thoracic Surgery·R R KlingmanT R DeMeester
Mar 3, 2010·Journal of the American Animal Hospital Association·Marjorie E MilneBen P Landon
Jun 1, 1992·Histopathology·G N SoosayM N Sheppard
Oct 3, 2018·Annals of the American Thoracic Society·Amany F ElbehairyDenis E O'Donnell
Mar 30, 2019·Case Reports in Anesthesiology·Ekaterini AmanitiVasilios Grosomanidis
Apr 11, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Fangfang GuoGuangfa Wang
May 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P D Slinger
Dec 20, 2003·Chest Surgery Clinics of North America·Jacob A GreenbergLarry R Kaiser
Mar 27, 2021·Journal of Chest Surgery·Abdel-Mohsen M HamadSaleh M Alorainy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved