Origin and evolution of the eukaryotic SSU processome revealed by a comprehensive genomic analysis and implications for the origin of the nucleolus

Genome Biology and Evolution
Jin-Mei FengJian-Fan Wen

Abstract

As a nucleolar complex for small-subunit (SSU) ribosomal RNA processing, SSU processome has been extensively studied mainly in Saccharomyces cerevisiae but not in diverse organisms, leaving open the question of whether it is a ubiquitous mechanism across eukaryotes and how it evolved in the course of the evolution of eukaryotes. Genome-wide survey and identification of SSU processome components showed that the majority of all 77 yeast SSU processome proteins possess homologs in almost all of the main eukaryotic lineages, and 14 of them have homologs in archaea but few in bacteria, suggesting that the complex is ubiquitous in eukaryotes, and its evolutionary history began with abundant protein homologs being present in archaea and then a fairly complete form of the complex emerged in the last eukaryotic common ancestor (LECA). Phylogenetic analysis indicated that ancient gene duplication and functional divergence of the protein components of the complex occurred frequently during the evolutionary origin of the LECA from prokaryotes. We found that such duplications not only increased the complex's components but also produced some new functional proteins involved in other nucleolar functions, such as ribosome biogenesis and even ...Continue Reading

References

Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·R A Young, J A Steitz
Dec 1, 1993·Protein Science : a Publication of the Protein Society·P Bhargava
Aug 29, 1997·Science·A G RussellP P Dennis
Apr 25, 2000·Science·A D OmerP P Dennis
Mar 14, 2001·Trends in Biochemical Sciences·C MayerO Poch
Feb 14, 2002·Nucleic Acids Research·Thean Hock TangAlexander Hüttenhofer
Jul 6, 2002·Science·Alexandra Stechmann, Thomas Cavalier-Smith
Sep 6, 2003·Current Biology : CB·Alexandra Stechmann, Thomas Cavalier-Smith
Oct 8, 2003·Systematic Biology·Stéphane Guindon, Olivier Gascuel
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Apr 28, 2004·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Eike StaubBernd Hinzmann
Jul 24, 2004·Biochemical Society Transactions·Julio Sáez-VasquezManuel Echeverría
Oct 19, 2004·Proceedings of the National Academy of Sciences of the United States of America·Tímea Gérczei, Carl C Correll
Dec 14, 2004·Eukaryotic Cell·Kara A BernsteinSusan J Baserga
Jan 22, 2005·Molecular Biology and Evolution·Lesley Collins, David Penny
Aug 18, 2005·Nucleic Acids Research·Kira S MakarovaEugene V Koonin
Mar 3, 2006·Nature·William Martin, Eugene V Koonin
Jan 19, 2007·Molecular Microbiology·Robert A BrittonCiarán Condon
Sep 29, 2007·Science·Hilary G MorrisonMitchell L Sogin
Apr 15, 2008·Cellular and Molecular Life Sciences : CMLS·A K HenrasY Henry
May 9, 2008·Molecular Biology and Evolution·Natalya YutinEugene V Koonin
Aug 22, 2008·Trends in Ecology & Evolution·Svetlana A Shabalina, Eugene V Koonin
Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Cymon J CoxT Martin Embley
Feb 27, 2009·Current Biology : CB·Andrew J Roger, Alastair G B Simpson
Apr 1, 2009·Molecular and Cellular Biology·Amy Jane TurnerNicholas James Watkins
Oct 31, 2009·RNA Biology·Manja Marz, Peter F Stadler
Mar 13, 2010·PloS One·Morgan N PriceAdam P Arkin
Oct 22, 2010·Nature·Nick Lane, William Martin
Nov 13, 2010·Science·Michael W GrayW Ford Doolittle
Feb 15, 2011·Wiley Interdisciplinary Reviews. RNA·Kathleen R PhippsSusan J Baserga
Dec 3, 2011·Molecular Biology and Evolution·Romain Derelle, B Franz Lang
Dec 7, 2011·Molecular Biology and Evolution·Michael Lynch
Jul 19, 2012·Annual Review of Microbiology·Laura A Katz

Related Concepts

Related Feeds

Archaeogenetics

Recent advances in genomic sequencing has led to the discovery of new strains of Archaea and shed light on their evolutionary history. Discover the latest research on Archaeogenetics here.