Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution.

Biology Direct
Thomas Cavalier-Smith

Abstract

The transition from prokaryotes to eukaryotes was the most radical change in cell organisation since life began, with the largest ever burst of gene duplication and novelty. According to the coevolutionary theory of eukaryote origins, the fundamental innovations were the concerted origins of the endomembrane system and cytoskeleton, subsequently recruited to form the cell nucleus and coevolving mitotic apparatus, with numerous genetic eukaryotic novelties inevitable consequences of this compartmentation and novel DNA segregation mechanism. Physical and mutational mechanisms of origin of the nucleus are seldom considered beyond the long-standing assumption that it involved wrapping pre-existing endomembranes around chromatin. Discussions on the origin of sex typically overlook its association with protozoan entry into dormant walled cysts and the likely simultaneous coevolutionary, not sequential, origin of mitosis and meiosis. I elucidate nuclear and mitotic coevolution, explaining the origins of dicer and small centromeric RNAs for positionally controlling centromeric heterochromatin, and how 27 major features of the cell nucleus evolved in four logical stages, making both mechanisms and selective advantages explicit: two init...Continue Reading

References

Nov 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·C R Woese, G E Fox
Aug 7, 1975·Nature·T Cavalier-tsmith
Sep 20, 1977·Journal of Molecular Evolution·C R Woese, G E Fox
May 1, 1991·Trends in Genetics : TIG·T Cavalier-Smith
Aug 7, 1987·Journal of Theoretical Biology·T Cavalier-Smith
May 23, 1985·Nature·T Cavalier-Smith
Aug 1, 1988·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·T Cavalier-Smith
Jan 1, 1987·Annals of the New York Academy of Sciences·T Cavalier-Smith
Jan 1, 1987·Cold Spring Harbor Symposia on Quantitative Biology·T Cavalier-Smith
Jul 1, 1974·Bio Systems·J Pickett-Heaps
Oct 1, 1974·The Journal of Cell Biology·B R Oakley, J D Dodge
Jan 1, 1966·Annual Review of Physiology·C De Duve, R Wattiaux
Sep 18, 1980·Nature·L M Van Valen, V C Maiorana
Jan 1, 1984·Bio Systems·J O Corliss
Jan 1, 1982·Annual Review of Biophysics and Bioengineering·T Cavalier-Smith
Jun 26, 1980·Nature·T Cavalier-Smith
Dec 1, 1993·Molecular Microbiology·J Hinnebusch, K Tilly
Jul 21, 1994·Nature·A S Kondrashov
Sep 29, 1995·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K Nasmyth
Aug 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·S M BarnsN R Pace
May 1, 1996·Trends in Biochemical Sciences·R S Gupta, G B Golding
Mar 24, 1998·Nature·W Martin, M Müller
Nov 11, 1998·Biological Reviews of the Cambridge Philosophical Society·T Cavalier-Smith
Apr 27, 1999·Trends in Biochemical Sciences·P López-Garćia, D Moreira
Aug 19, 1999·Protein Science : a Publication of the Protein Society·K S MakarovaE V Koonin
Mar 31, 2000·Trends in Plant Science·T Cavalier-Smith
Jul 21, 2000·Proceedings. Biological Sciences·M J Beaton, T Cavalier-Smitht
Dec 20, 2000·Proceedings of the National Academy of Sciences of the United States of America·I Arkhipova, M Meselson
Aug 3, 2001·Nature Cell Biology·C Rotte, W Martin
Mar 1, 1967·Journal of Theoretical Biology·L Sagan
Jan 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·Hyman Hartman, Alexei Fedorov
Jan 31, 2002·Current Biology : CB·T Cavalier-Smith
Feb 12, 2002·International Journal of Systematic and Evolutionary Microbiology·T Cavalier-Smith
Mar 28, 2002·Journal of Molecular Biology·Detlef D LeipeL Aravind

❮ Previous
Next ❯

Citations

Oct 20, 2011·Current Genetics·Matej Vesteg, Juraj Krajčovič
Jul 16, 2013·Plant Reproduction·Erik Wijnker, Arp Schnittger
Sep 3, 2013·Plant Reproduction·Elvira Hörandl, Franz Hadacek
Apr 25, 2012·Protoplasma·František BaluškaPeter Barlow
Aug 16, 2013·Journal of Human Genetics·Sergio Ulhoa DaniGerhard Franz Walter
Jul 14, 2010·Genome Biology and Evolution·Tal DaganWilliam Martin
May 24, 2013·Genome Biology and Evolution·Miguel GaravísAlfredo Villasante
Jul 8, 2011·Clinical Microbiology Reviews·Antonio R L TeixeiraNadjar Nitz
Jun 13, 2012·Microbiology and Molecular Biology Reviews : MMBR·Miklós MüllerWilliam F Martin
Aug 25, 2010·Biology Direct·Jeferson Gross, Debashish Bhattacharya
Jul 1, 2011·Biology Direct·William F Martin
Dec 19, 2013·Archaea : an International Microbiological Journal·Patrick Forterre
Jan 9, 2014·Molecular Biology and Evolution·Nicolas C RochetteManolo Gouy
May 8, 2014·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Christophe TatoutKatja Graumann
Jul 19, 2012·Annual Review of Microbiology·Laura A Katz
Nov 12, 2010·Molecular Membrane Biology·Marek Elias
Aug 24, 2011·The Journal of Cell Biology·Bill Wickstead, Keith Gull
Jun 13, 2012·The Journal of Cell Biology·Francesc R Garcia-Gonzalo, Jeremy F Reiter
Jun 15, 2011·The Journal of Cell Biology·Mark C FieldMichael P Rout
Oct 7, 2015·Current Biology : CB·John M Archibald
Jan 17, 2012·Current Opinion in Cell Biology·Silvija Bilokapic, Thomas U Schwartz
Feb 17, 2015·Current Biology : CB·Reza FarhadifarDaniel J Needleman
Oct 29, 2014·BMC Biology·David A Baum, Buzz Baum
Apr 15, 2015·Biochimie·Toni Gabaldón, Alexandros A Pittis
Sep 3, 2014·Journal of Molecular Evolution·David PennySimon J Cox
Jul 15, 2011·Molecular Microbiology·Stephan Gruber
Aug 6, 2013·Wiley Interdisciplinary Reviews. RNA·Alexander F PalazzoStefan P Tarnawsky
Aug 22, 2014·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Søren Overballe-Petersen, Eske Willerslev
Jul 17, 2015·Journal of Molecular Evolution·Masaharu TakemuraHiroyuki Ogata
Oct 13, 2015·Trends in Ecology & Evolution·Purificación López-García, David Moreira
Dec 3, 2014·Current Biology : CB·Shelley SazerDaniel Needleman
Sep 2, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·James McInerneyMary J O'Connell
Nov 23, 2011·Biochemical Society Transactions·Ricardo A FigueroaEinar Hallberg
Sep 9, 2010·Essays in Biochemistry·Jan PostbergThomas Cremer
Jul 6, 2010·Biochimica Et Biophysica Acta·Markus T Bohnsack, Enrico Schleiff
Aug 11, 2015·Frontiers in Microbiology·Patrick Forterre
May 9, 2015·European Journal of Cell Biology·Ralph GräfIrene Meyer
May 7, 2013·Nucleus·Barbara Boettcher, Yves Barral
Feb 11, 2014·Current Opinion in Cell Biology·Damien P DevosMark C Field

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Methods Mentioned

BETA
GTPases
GTPase
acetylation
PCR
ubiquitination
small
by

Software Mentioned

MreB
BLASTP
BLAST
Thermophily
ParM

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