Origins, Admixture Dynamics, and Homogenization of the African Gene Pool in the Americas.

Molecular Biology and Evolution
M. H. GouveiaEduardo Tarazona-Santos

Abstract

The Transatlantic Slave Trade transported more than 9 million Africans to the Americas between the early 16th and the mid-19th centuries. We performed a genome-wide analysis using 6,267 individuals from 25 populations to infer how different African groups contributed to North-, South-American, and Caribbean populations, in the context of geographic and geopolitical factors, and compared genetic data with demographic history records of the Transatlantic Slave Trade. We observed that West-Central Africa and Western Africa-associated ancestry clusters are more prevalent in northern latitudes of the Americas, whereas the South/East Africa-associated ancestry cluster is more prevalent in southern latitudes of the Americas. This pattern results from geographic and geopolitical factors leading to population differentiation. However, there is a substantial decrease in the between-population differentiation of the African gene pool within the Americas, when compared with the regions of origin from Africa, underscoring the importance of historical factors favoring admixture between individuals with different African origins in the New World. This between-population homogenization in the Americas is consistent with the excess of West-Cent...Continue Reading

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Citations

Sep 26, 2020·Frontiers in Genetics·Vania PereiraLeonor Gusmão
Dec 16, 2020·American Journal of Human Genetics·Steven J MichelettiJoanna L Mountain
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Oct 12, 2021·Frontiers in Genetics·Ana Cecília Guimarães AlvesVictor Borda
Oct 16, 2021·Human Genetics·Karina Lezirovitz, Regina Célia Mingroni-Netto

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