Origins and genetic legacies of the Caribbean Taino

Proceedings of the National Academy of Sciences of the United States of America
Hannes SchroederEske Willerslev

Abstract

The Caribbean was one of the last parts of the Americas to be settled by humans, but how and when the islands were first occupied remains a matter of debate. Ancient DNA can help answering these questions, but the work has been hampered by poor DNA preservation. We report the genome sequence of a 1,000-year-old Lucayan Taino individual recovered from the site of Preacher's Cave in the Bahamas. We sequenced her genome to 12.4-fold coverage and show that she is genetically most closely related to present-day Arawakan speakers from northern South America, suggesting that the ancestors of the Lucayans originated there. Further, we find no evidence for recent inbreeding or isolation in the ancient genome, suggesting that the Lucayans had a relatively large effective population size. Finally, we show that the native American components in some present-day Caribbean genomes are closely related to the ancient Taino, demonstrating an element of continuity between precontact populations and present-day Latino populations in the Caribbean.

References

Oct 1, 1985·American Journal of Physical Anthropology·D C WallaceW C Knowler
May 13, 2003·American Journal of Physical Anthropology·C Lalueza-FoxJ Bertranpetit
Jan 22, 2004·Bioinformatics·Emmanuel ParadisKorbinian Strimmer
Oct 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·Sohini RamachandranL Luca Cavalli-Sforza
Sep 6, 2007·PloS One·Erika TammRipan S Malhi
Jul 23, 2008·BMC Evolutionary Biology·Isabel MendizabalDavid Comas
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
Aug 4, 2009·Genome Research·David H AlexanderKenneth Lange
May 7, 2010·Proceedings of the National Academy of Sciences of the United States of America·Katarzyna BrycHarry Ostrer
Jun 3, 2010·Cold Spring Harbor Protocols·Matthias Meyer, Martin Kircher
Nov 19, 2010·PloS One·Mirna KirinJames F Wilson
Oct 25, 2011·Nucleic Acids Research·Martin KircherMatthias Meyer
Dec 6, 2011·Nature Methods·Olivier DelaneauJean-François Zagury
Feb 1, 2012·PLoS Genetics·Daniel John LawsonDaniel Falush
May 12, 2012·BMC Genomics·Mikkel SchubertLudovic Orlando
May 16, 2012·Journal of Forensic Sciences·Jamie L WilsonBruce A Jackson
Jul 18, 2012·Nature·David ReichAndrés Ruiz-Linares
Aug 14, 2012·American Journal of Human Genetics·Trevor J PembertonJun Z Li
Sep 11, 2012·Genetics·Nick PattersonDavid Reich
Nov 19, 2013·PLoS Genetics·Andrés Moreno-EstradaCarlos D Bustamante
Jan 5, 2014·PLoS Genetics·Simon GravelCarlos D Bustamante
Jul 22, 2014·American Journal of Physical Anthropology·Miguel G VilarUNKNOWN Genographic Consortium
Nov 14, 2014·American Journal of Human Biology : the Official Journal of the Human Biology Council·Nicole MadrilejoJada Benn Torres
Nov 26, 2014·BMC Bioinformatics·Thorfinn KorneliussenRasmus Nielsen
Dec 10, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·F MendiscoM F Deguilloux
Feb 28, 2015·GigaScience·Christopher C ChangJames J Lee
Mar 11, 2015·Proceedings of the National Academy of Sciences of the United States of America·Hannes SchroederM Thomas P Gilbert
Jun 19, 2015·Nature·Morten RasmussenEske Willerslev
Jul 22, 2015·Nature·Pontus SkoglundDavid Reich
Oct 4, 2015·Nature·UNKNOWN 1000 Genomes Project ConsortiumGonçalo R Abecasis
Oct 9, 2015·PloS One·Jada Benn TorresUNKNOWN Genographic Consortium
Feb 13, 2016·BMC Research Notes·Mikkel SchubertLudovic Orlando
Apr 7, 2016·PLoS Genetics·Fernando RacimoMontgomery Slatkin
Nov 24, 2017·Genetics·Joshua G Schraiber

❮ Previous
Next ❯

Citations

May 8, 2018·Genome Research·Alberto Gómez-CarballaAntonio Salas
May 8, 2019·Proceedings of the National Academy of Sciences of the United States of America·Hannes SchroederMorten E Allentoft
Jul 28, 2019·Molecular Biology and Evolution·Chiara BarbieriLars Fehren-Schmitz
Oct 11, 2019·American Journal of Physical Anthropology·Fanny MendiscoMarie-France Deguilloux
Nov 12, 2019·Molecular Biology and Evolution·Maria A Nieves-ColónAnne C Stone
Jan 12, 2020·Scientific Reports·Ann H RossColleen B Young
Nov 10, 2018·Science·J Víctor Moreno-MayarEske Willerslev
Dec 21, 2018·European Journal of Human Genetics : EJHG·Leonard RutgersHannes Schroeder
Aug 1, 2018·Scientific Reports·Cesar Fortes-LimaBeatriz Marcheco-Teruel
Jun 6, 2020·Science·Kathrin NägeleHannes Schroeder
Mar 22, 2019·Molecular Biology and Evolution·Guido Alberto Gnecchi-RusconeDavide Pettener
May 11, 2020·Cell·Nathan NakatsukaLars Fehren-Schmitz
Dec 29, 2020·Nature·Daniel M FernandesDavid Reich
Mar 25, 2021·Cell·Marco Rosario CapodiferroAlessandro Achilli
Jun 18, 2021·Nature·Eske Willerslev, David J Meltzer
Sep 24, 2021·Nature·Alexander G IoannidisAndrés Moreno-Estrada
Oct 12, 2021·Frontiers in Genetics·Lucía SpangenbergHugo Naya

❮ Previous
Next ❯

Methods Mentioned

BETA
PCRs
PCR

Software Mentioned

ChromoPainter
EIGENSOFT
bwa
Clovis
FigTree
SHAPEIT
ANGSD
samtools
R
ADMIXTURE

Related Concepts

Related Feeds

Ancient DNA

Ancient DNA sequences are able to offer valuable insights into molecular evolutionary processes, but are notoriously difficult to analyze due to molecular damage and exogenous dna contamination. Discover the latest research on Ancient DNA here.

BioHub - Researcher Network

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.