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Origins and impacts of new exons

bioRxiv

Sep 18, 2014

Jason Merkin*Christopher B Burge

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Abstract

Mammalian genes are typically broken into several protein-coding and non-coding exons, but the evolutionary origins and functions of new exons are not well understood. Here, we analyzed patterns of exon gain using deep cDNA sequencing data from several mammals and one bird, identifying ...read more

Mentioned in this Paper

Gene Expression
RNA Polymerase II
RNA Splicing
Nucleosomes
Introns
Nucleosome Location
Exons
Nuclear mRNA Cis Splicing, via Spliceosome
Sequencing
5' Untranslated Regions
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  • Origins and impacts of new exons

    bioRxiv

    Sep 18, 2014

    Jason Merkin*Christopher B Burge

    PMID: 990009282

    DOI: 10.1101/009282

    Abstract

    Mammalian genes are typically broken into several protein-coding and non-coding exons, but the evolutionary origins and functions of new exons are not well understood. Here, we analyzed patterns of exon gain using deep cDNA sequencing data from several mammals and one bird, identifying ...read more

    Mentioned in this Paper

    Gene Expression
    RNA Polymerase II
    RNA Splicing
    Nucleosomes
    Introns
    Paper Details
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