Origins of nerve fibers containing nitric oxide synthase in the rat celiac-superior mesenteric ganglion

Cell and Tissue Research
T DomotoY Yasui

Abstract

The origin of nitric oxide synthase-containing nerve fibers in rat celiac-superior mesenteric ganglion was examined using retrograde tracing techniques combined with the immunofluorescence method. Fluoro-Gold was injected into the celiac-superior mesenteric ganglion. Neuronal cell bodies retrogradely labeled with Fluoro-Gold in the thoracic spinal cord, the dorsal root ganglia at the thoracic level, the nodose ganglion, and the intestine from the duodenum to the proximal colon were examined for nitric oxide synthase immunoreactivity. About 60% of sympathetic preganglionic neurons in the intermediolateral nucleus projecting to the celiac-superior mesenteric ganglion were immunoreactive for nitric oxide synthase, as were approximately 27% of nodose ganglion neurons and about 65% of dorsal root ganglion neurons projecting to the celiac-superior mesenteric ganglion. Neurons projecting to the celiac-superior mesenteric ganglion were found in the myenteric plexus of the small and large intestine. In the proximal colon, about 23% of such neurons were immunoreactive for nitric oxide synthase. However, in the small intestine, no immunoreactivity was found in these neurons.

References

Nov 10, 2001·Brain Research·M L WeissJ Huang
Jan 27, 1998·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·I StoyanovaD W Scheuermann
Jul 8, 2009·Autonomic Neuroscience : Basic & Clinical·Caroline Fasano, Jean-Pierre Niel
Apr 26, 2019·The Journal of Comparative Neurology·Charlotte L KaestnerDonald B Hoover
Apr 9, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·C BossoneT Shea-Donohue

Citations

Apr 15, 1991·The Journal of Comparative Neurology·Y AimiH Kimura
May 8, 1989·The Journal of Comparative Neurology·C R AndersonO Srb-Christie
Aug 1, 1989·Journal of the Autonomic Nervous System·H Kuramoto, J B Furness
Jul 5, 1988·Brain Research·A M StrackA D Loewy
Jan 1, 1994·Journal of the Autonomic Nervous System·J B Furness, C R Anderson
Mar 1, 1993·Cell and Tissue Research·K McConalogue, J B Furness
Apr 2, 1993·Neuroscience Letters·M A VizzardW C de Groat
Jul 1, 1993·Neuroreport·D BlottnerH G Baumgarten
Feb 1, 1993·Journal of the Autonomic Nervous System·H R Berthoud, T L Powley

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