Ornitine-dependent mechanisms of muscle fatigue correction and recovery from physical activity

Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
S V Okovityi, E B Shustov

Abstract

The article analyzes the literature data characterizing modern concepts of the mechanisms of muscle fatigue and metabolic features of recovery processes after exhausting loads. The significance of transient hyperammonium in the formation of the developed complex of fatigue manifestations in the central and peripheral links of motor units, its pathogenetic links with oxygen debt, lactacidosis, violation of ATP resynthesis, deficiency of energy-supplying substrates in working skeletal muscles, damage to muscle fibre structures, and dysfunction of various parts of the CNS is shown. The necessity of correction of hyperammoniemia associated with physical activity has been confirmed to reduce the speed of formation and expression of fatigue feeling, to reduce the risks of development of fatigue and overtraining states in sportsmen and to ensure effective course of recovery processes after exhausting physical activity. It was revealed that ornithine-containing preparations can be used for correction of post-load hyperammonium and acceleration of recovery processes. The data characterizing the high efficiency of L-ornitine-L-aspartate in sports medicine practice are presented.

References

Sep 1, 1979·The American Journal of Physiology·R A Meyer, R L Terjung
Mar 9, 1976·European Journal of Applied Physiology and Occupational Physiology·V BrodanD Tomková
May 1, 1990·International Journal of Sports Medicine·E W Banister, B J Cameron
Aug 1, 1990·The American Journal of Physiology·T E GrahamB Saltin
Aug 1, 1986·Clinical Physiology·A KatzJ Wahren
May 1, 1985·Journal of Applied Physiology·D H SnowS P Gash
Aug 1, 1985·Clinical Physiology·L S ErikssonJ Wahren
May 1, 1973·The American Journal of Physiology·G A BrooksR G Cassens
Jan 1, 1983·Medicine and Science in Sports and Exercise·B J Mutch, E W Banister
Jul 1, 1980·The American Journal of Physiology·R A Meyer, R L Terjung
Jun 12, 1998·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·H K StrüderK Weber
Nov 14, 1998·The American Journal of Physiology·F YoshizawaL S Jefferson
Apr 6, 1999·International Journal of Sports Medicine·W AmentG J Verkerke
Aug 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C RoseR F Butterworth
Oct 31, 2002·Equine Veterinary Journal. Supplement·C M McGowanR J Rose
May 17, 2003·Medicine and Science in Sports and Exercise·Hannu T PitkanenAntti A Mero
Dec 1, 1964·The American Journal of Physiology·R H BARNESR B BRADFIELD
Feb 9, 2010·Progress in Neurobiology·Daniel J WilkinsonPeter W Watt
Aug 28, 2012·Metabolism: Clinical and Experimental·Maria M AdevaCristóbal Donapetry
Nov 8, 2012·Journal of Nutritional Science and Vitaminology·Kazuyo TujiokaHidehiko Yokogoshi
Jul 31, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Lance L Stein, Marty T Sellers
Oct 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jia QiuSrinivasan Dasarathy
Dec 5, 2015·American Journal of Physiology. Gastrointestinal and Liver Physiology·John McDanielSrinivasan Dasarathy
Feb 1, 2018·Nutrients·Jing LiuSeong-Tshool Hong
Mar 13, 2019·Journal of Animal Physiology and Animal Nutrition·Rachel A Stern, Paul E Mozdziak

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