Abstract
Incidence rates for human papillomavirus positive oropharyngeal cancer (HPV-positive OPC) have significantly increased in numerous developed countries in recent decades. Fortunately, HPV-positive OPC has improved survival relative to HPV-negative OPC. Given these incidence trends and survival differences, we hypothesized that OPC survivorship has increased in affected populations over time. Poisson and Cox regression models were used to examine incidence and OPC survivorship trends in a population-based prospective registry, the Danish Cancer Registry. In Denmark, OPC incidence (p<0.001) and median survival (p<0.001) significantly increased from 1977 to 2012. Consequently, the number of 5-year OPC survivors in the Danish population increased from 72 in 1980 to 1311 in 2010. The long-term sequelae of curative therapy in the growing number of OPC survivors will need to be evaluated to address their unique survivorship needs.
References
Dec 1, 1993·Journal of Periodontology·Z W Yusof, M M Bakri
Sep 23, 2006·International Journal of Cancer. Journal International Du Cancer·Lalle HammarstedtEva Munck-Wikland
Feb 14, 2008·Journal of the National Cancer Institute·Carole FakhryMaura L Gillison
Jan 24, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Claire F SnyderCraig C Earle
Mar 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Pernille LassenJens Overgaard
Mar 17, 2010·Vaccine·Angela M HongBarbara R Rose
Jun 10, 2010·The New England Journal of Medicine·K Kian AngMaura L Gillison
Aug 4, 2011·Scandinavian Journal of Public Health·Marianne Lundkjær Gjerstorff
Oct 5, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Feb 19, 2013·Journal of Cancer Survivorship : Research and Practice·Kathryn E WeaverNoreen M Aziz
Nov 20, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Mar 14, 2014·International Journal of Cancer. Journal International Du Cancer·H MirghaniJ Lacau St Guily
Oct 7, 2014·International Journal of Cancer. Journal International Du Cancer·Emilie GarnaesChristian von Buchwald
Citations
Mar 8, 2016·Cancer·Mira A PatelCarole Fakhry
May 18, 2016·Cancer·Eleni M RettigCarole Fakhry
Aug 18, 2016·Oral Oncology·Gypsyamber D'SouzaCarole Fakhry
Aug 24, 2016·Acta Oncologica·Malene F SvahnSusanne K Kjaer
May 10, 2019·The Laryngoscope·Farhoud FarajiCarole Fakhry
Oct 24, 2017·Acta Oncologica·Jakob Schmidt JensenChristian von Buchwald
Jan 11, 2020·Head & Neck·David M CognettiKelly M Malloy
Dec 28, 2016·Carcinogenesis·Camille RaginEmanuela Taioli
Sep 21, 2018·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Hani Z MarzoukiHadi Seikaly
Dec 3, 2016·Nature Reviews. Disease Primers·Mark SchiffmanSilvia Franceschi
Nov 18, 2018·Cancer·Danielle F EytanCarole Fakhry
May 2, 2018·Cancer·Melina J WindonCarole Fakhry
Sep 13, 2017·Laryngoscope Investigative Otolaryngology·Farhoud FarajiCarole Fakhry
Dec 25, 2015·Cancer Prevention Research·Carole FakhryRaphael P Viscidi
Jul 22, 2021·Head & Neck·Melina J WindonEleni M Rettig
Jun 23, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Raiany Santos CarvalhoAna Carolina de Carvalho