Oropouche fever epidemic in Northern Brazil: epidemiology and molecular characterization of isolates

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Helena Baldez VasconcelosPedro F C Vasconcelos

Abstract

Oropouche fever virus is an important arbovirus associated with febrile disease that re-emerged in 2006 in several municipalities of Pará State, Bragantina region, Amazon, Brazil, 26 years after the last epidemic. To investigate an Oropouche fever outbreak in this region. A serologic survey and prospective study of acute febrile cases were performed in Magalhães Barata (urban and rural areas) and Maracanã (rural area) municipalities. Serology (IgM-ELISA and hemagglutination-inhibition [HI]), virus isolation, RT-PCR and real-time-PCR were used to confirm Oropouche virus (OROV) as responsible for the febrile outbreaks. Real-time-PCR showed high titers of OROV in acute-phase serum samples from febrile patients. From 113 of 119 acutely febrile patients with paired serum samples, OROV infections was confirmed by serologic conversion (n=76) or high titers (n=37) for both HI and IgM-ELISA. Patients had a febrile disease characterized by headache, chills, dizziness, photophobia, myalgia, nausea, and vomiting. Females and children under 15 years of age were most affected. Nucleotide sequencing of six OROV isolates identified that genotype II was associated with the human disease epidemic. Oropouche fever, which has re-emerged in the Bra...Continue Reading

References

Apr 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·K C HyamsD M Watts
Feb 17, 2000·The Journal of General Virology·M F SaeedA D Barrett
Oct 12, 2001·Journal of Medical Virology·P F VasconcelosJ F Travassos Da Rosa
Jul 5, 2003·Journal of Clinical Microbiology·Manfred WeidmannFrank T Hufert
Nov 1, 1962·Transactions of the Royal Society of Tropical Medicine and Hygiene·L SPENCEW G DOWNS
Jan 1, 1955·Proceedings of the Society for Experimental Biology and Medicine·D H CLARKE, J CASALS
Dec 2, 2005·Emerging Infectious Diseases·Márcio Roberto Teixeira NunesPedro Fernando da Costa Vasconcelos
Jun 8, 2007·Emerging Infectious Diseases·Raimundado Socorro da Silva AzevedoPedro Fernando da Costa Vasconcelos

❮ Previous
Next ❯

Citations

Sep 29, 2011·PLoS Neglected Tropical Diseases·Patricia V AguilarTadeusz J Kochel
Dec 8, 2009·Emerging Infectious Diseases·Maria Paula G MourããoLuiz Tadeu M Figueiredo
May 3, 2011·Emerging Infectious Diseases·Helena Baldez VasconcelosPedro F C Vasconcelos
Oct 25, 2012·Emerging Infectious Diseases·Chantal ReuskenMarion Koopmans
Apr 12, 2012·The American Journal of Tropical Medicine and Hygiene·Michele de Souza BastosMaria Paula Gomes Mourão
Apr 6, 2011·Archives of Virology·Cintia Lopes de Brito MagalhãesPaulo César Peregrino Ferreira
May 28, 2014·Archives of Virology·Fernanda Caetano CaminiCintia Lopes de Brito Magalhães
Aug 24, 2010·Virus Research·Alcir Humberto RodriguesEurico Arruda
Mar 19, 2016·Vector Borne and Zoonotic Diseases·Pedro F C Vasconcelos, Charles H Calisher
Mar 5, 2015·The Journal of General Virology·Natasha L Tilston-LunelRichard M Elliott
Jul 31, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Natalie CletonChantal Reusken
Aug 13, 2013·Antiviral Research·Simon CarpenterBethan V Purse
Dec 28, 2016·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Heverton Leandro Carneiro DutraLuciano Andrade Moreira
Jan 24, 2017·PLoS Neglected Tropical Diseases·Cristiane W CardosoGuilherme S Ribeiro
May 25, 2016·The American Journal of Tropical Medicine and Hygiene·Juan-Carlos NavarroMarcio R T Nunes
Nov 1, 2015·Memórias do Instituto Oswaldo Cruz·Belgath Fernandes CardosoRenata Dezengrini Slhessarenko
Jun 25, 2015·Revista Da Sociedade Brasileira De Medicina Tropical·Luiz Tadeu Moraes Figueiredo
Jun 11, 2015·Revista Da Sociedade Brasileira De Medicina Tropical·Maria Paula Gomes MourãoLuiz Tadeu Moraes Figueiredo
Apr 5, 2018·Viruses·Hercules SakkasChrissanthy Papadopoulou
Dec 25, 2015·Journal of Virology·Natasha L Tilston-LunelRichard M Elliott
Nov 26, 2014·PloS One·Kinga M SulyokMiklós Gyuranecz
Dec 6, 2019·Journal of Virology·Bernardo GutierrezOliver G Pybus
Jan 11, 2019·PloS One·Monika Szymańska-CzerwińskaKrzysztof Niemczuk
May 23, 2018·Current Clinical Microbiology Reports·Víctor Hugo Peña-GarcíaRebecca C Christofferson
Apr 8, 2011·Emerging Infectious Diseases·Hendrik I J RoestFred G van Zijderveld
Feb 3, 2015·Journal of Investigative and Clinical Dentistry·Endang W BachtiarSiti M Surono Akbar
Mar 2, 2010·Cadernos de saúde pública·Marcio Roberto Teixeira NunesPedro Fernando da Costa Vasconcelos
Dec 1, 2019·Scientific Reports·Euzébio de OliveiraPedro Fernando Costa Vasconcelos
Sep 28, 2017·PLoS Neglected Tropical Diseases·Camila LorenzLincoln Suesdek
Jun 8, 2017·Memórias do Instituto Oswaldo Cruz·Felipe Gomes NavecaPedro Fernando da Costa Vasconcelos
Dec 7, 2018·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Márcio Roberto Teixeira NunesGustavo Palacios

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Emerging Infectious Diseases
Márcio R T NunesPedro Fernando da Costa Vasconcelos
Emerging Infectious Diseases
Raimundado Socorro da Silva AzevedoPedro Fernando da Costa Vasconcelos
Emerging Infectious Diseases
Helena Baldez VasconcelosPedro F C Vasconcelos
Emerging Infectious Diseases
Maria Paula G MourããoLuiz Tadeu M Figueiredo
© 2021 Meta ULC. All rights reserved