Oropouche virus detection in saliva and urine

Memórias do Instituto Oswaldo Cruz
Valdinete Alves do NascimentoFelipe Gomes Naveca

Abstract

Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.

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Datasets Mentioned

BETA
MN419356
MN419357
MN419358

Methods Mentioned

BETA
PCR

Software Mentioned

MUSCLE
MEGA X
Geneious
MrBayes
FigTree
PhyML

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