Orthogonal Chemical Modification of Template-Synthesized Nanostructures with DNA

Journal of the American Chemical Society
Taegon OhChad A Mirkin

Abstract

Very few chemical strategies for the selective functionalization of nanostructures have been developed despite their potential for controlling high-order assembly processes. We report a novel approach for the selective chemical functionalization and localized assembly of one-dimensional nanostructures (rods), based upon the systematic activation (DNA functionalization) and passivation (self-assembled monolayers) of specific surface sites through the use of orthogonal chemical reactions on electrochemically grown metal nanorod arrays in porous anodic aluminum oxide templates. The ability to orthogonally functionalize the ends or the side of a nanorod, as well as the gaps between two rods, with different DNA strands allows one to synthesize nanostructure assemblies that would be difficult to realize any other way and that could ultimately be utilized for making a wide variety of device architectures.

References

Oct 6, 2001·Science·S R Nicewarner-PenaM J Natan
Feb 23, 2002·Science·So-Jung ParkChad A Mirkin
Aug 31, 2002·Science·YunWei Charles CaoChad A Mirkin
Sep 13, 2003·Nature Materials·Aliasger K SalemKam W Leong
Jan 17, 2004·Science·Sungho ParkChad A Mirkin
Jul 5, 2005·Science·Lidong QinChad A Mirkin
May 20, 2006·Science·Nathaniel L RosiChad A Mirkin
Jul 20, 2006·Journal of the American Chemical Society·Xiaoyang XuChad A Mirkin
Aug 3, 2006·Journal of the American Chemical Society·Asaf SalantUri Banin
Nov 30, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Bridget WildtPeter C Searson
Dec 15, 2006·Analytical Chemistry·Sarah J HurstChad A Mirkin
May 10, 2007·Journal of the American Chemical Society·P PramodK George Thomas
Jul 10, 2007·Nature Materials·Zhihong NieMichael Rubinstein
Jul 26, 2008·Nature Nanotechnology·Tihana MirkovicGeoffrey A Ozin
May 16, 2009·Nature Protocols·Matthew J BanholzerChad A Mirkin
Oct 5, 2010·Nature Materials·Matthew R JonesChad A Mirkin
Dec 24, 2011·Journal of the American Chemical Society·Liguang XuNicholas A Kotov
Jul 20, 2012·Advanced Materials·Evelyn AuyeungChad A Mirkin
Nov 7, 2012·Nature·Yufeng WangDavid J Pine
May 18, 2013·Angewandte Chemie·Andrew J SenesiChad A Mirkin
May 21, 2013·Nature Materials·Chuan ZhangChad A Mirkin
Jul 3, 2013·Advanced Materials·Tuncay OzelChad A Mirkin
Oct 29, 2013·Nature Communications·Wei MaNicholas A Kotov
Feb 24, 2015·Science·Matthew R JonesChad A Mirkin
Mar 17, 2015·Proceedings of the National Academy of Sciences of the United States of America·Aleksandar F Radovic-MorenoSergei M Gryaznov
Mar 24, 2015·Nature Nanotechnology·Tuncay OzelChad A Mirkin
Apr 2, 2015·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey D BrodinChad A Mirkin
Apr 14, 2015·Advanced Materials·Jessie C KuChad A Mirkin
Jul 21, 2015·Journal of the American Chemical Society·Yufeng WangDavid J Pine
Jan 23, 2016·Nature Materials·Michael A BolesDmitri V Talapin
May 19, 2016·ACS Nano·Benjamin D MyersVinayak P Dravid
Nov 29, 2016·Nature Nanotechnology·Liaoyong WenYong Lei
Jun 14, 1999·Angewandte Chemie·Colin J LowethPeter G Schultz

❮ Previous
Next ❯

Citations

Jan 17, 2020·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Junkai ZhaoZhanhu Guo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.