Orthogonal polarization technique in the assessment of human skin microcirculation

International Journal of Dermatology
Omar LupiEliete Bouskela

Abstract

The "gold standard" for the study of the in vivo microcirculation is intravital microscopy. The recently developed method of orthogonal polarization of light [orthogonal polarization spectral (OPS) imaging] allows for the in vivo transcutaneous evaluation of the microcirculation without the need for invasive surgical procedures. The application of polarized light originating from a 100 W halogen tungsten lamp is able to penetrate tissues at a depth of up to 3 mm, and generates reissued light from this depth. The evaluation of this depolarized light, from a deeper origin, may be carried out separately from the light reflected by the more superficial layers of the tissue under study because this light retains photon polarization, whereas the former light undergoes real depolarization. The process of validation of the OPS technique, when compared with intravital microscopy, the "gold standard" for the in vivo observation of the microcirculation, has shown that it is as effective and reliable as the gold standard, reaching the same resolution level in the visualization of blood vessels, but without the need for invasive surgical procedures. The OPS technique is a very promising tool for dermatologists and researchers, especially in...Continue Reading

References

Jun 1, 1997·Biomedizinische Technik. Biomedical Engineering·T KlysczH Zeintl
Mar 15, 2000·Transplantation Proceedings·S OkamotoK Messmer
Aug 10, 2000·Neoplasia : an International Journal for Oncology Research·P VajkoczyM D Menger
Oct 3, 2000·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·K MessmerC Hammer
Apr 12, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·Aubrey E TaylorPeyton Paisley
Oct 23, 2002·International Journal of Dermatology·Stephen M Milner
Nov 12, 2002·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·D ErdmannB Klitzman
Mar 23, 2004·Journal of Anatomy·S SangiorgiM Raspanti
Mar 19, 2005·Burns : Journal of the International Society for Burn Injuries·Stephen M MilnerRoger J Bick
Jun 4, 2005·Microsurgery·Paul J Matheson, R Neal Garrison
Jun 9, 2005·Best Practice & Research. Clinical Rheumatology·Maurizio CutoloAlberto Sulli
Mar 25, 2006·Physiological Research·V CernýR Pařízková
Apr 22, 2006·Rheumatology·P M Houtman, T L T A Jansen
May 9, 2006·Journal of Vascular Surgery·Carlos Eduardo Virgini-MagalhãesEliete Bouskela
Jul 11, 2006·Zeitschrift für Rheumatologie·M CutoloC Pizzorni
Aug 25, 2006·The International Journal of Lower Extremity Wounds·M L IabichellaG Mosti

❮ Previous
Next ❯

Citations

Aug 7, 2010·Intensive Care Medicine·Daniel De BackerJean-Louis Vincent
Jun 7, 2011·Archives of Dermatological Research·Ivan SemenovitchEliete Bouskela
Aug 15, 2009·Diabetes/metabolism Research and Reviews·Clare Y L Chao, Gladys L Y Cheing
Apr 17, 2016·Photodiagnosis and Photodynamic Therapy·Iftikhar AhmadMasroor Ikram
May 26, 2017·Journal of Biophotonics·Rani Toll JohnChris D Anderson
Jan 26, 2010·Annals of Plastic Surgery·Ole GoertzStefan Langer
Jul 2, 2010·Journal of Lower Genital Tract Disease·Daron G FerrisCarlos Santos
Jun 14, 2013·Biomedical Optics Express·Xu FengEnyao Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.