Orthopaedic surgery in patients with rheumatoid arthritis over 20 years: prevalence and predictive factors of large joint replacement

Annals of the Rheumatic Diseases
M C KapetanovicK Eberhardt

Abstract

To study the prevalence of orthopaedic surgery and to evaluate possible predictive factors for large joint replacements in patients with early rheumatoid arthritis (RA). A cohort of 183 patients (116 (63.4%) female) with early RA was monitored for 16-20 years after recruitment during 1985-9. Mean (SD) age of patients 51.4 (12.4) years; mean (SD) duration of symptoms before inclusion 12 (7) months and mean (SD) duration of follow-up 16 (4) years. Occurrence of orthopaedic surgery was recorded continuously. A first prosthesis of a large joint (shoulder, elbow, wrist, hip, knee or ankle) was used as outcome variable in the predictive analyses. In total, 386 orthopaedic interventions were performed in 106/183 (58%) patients during follow-up and a large joint replacement was performed in 44/183 (24%) patients. Using a Cox regression model, it was shown that Health Assessment Questionnaire, C-reactive protein and erythrocyte sedimentation rate at inclusion, and radiographic changes in small joints after 1 year, were associated with an increased risk of receiving prosthesis of large joints. In this cohort of patients with RA monitored from early disease stage, orthopaedic surgical procedures were performed in more than half of the pat...Continue Reading

Citations

Sep 6, 2012·Rheumatology·Debbie Ehrmann FeldmanMichal Abrahamowicz
Jul 23, 2014·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Susan M GoodmanHassan Ghomrawi
Nov 10, 2012·Rheumatic Diseases Clinics of North America·Susan M Goodman, Stephen Paget
Nov 15, 2011·Reumatología clinica·Sara Manrique ArijaAntonio Fernández Nebro
Dec 25, 2015·Best Practice & Research. Clinical Rheumatology·Susan M Goodman, Mark A Figgie
May 14, 2011·Arthritis and Rheumatism·Nicholas R JonesAlexander J Szalai
Apr 6, 2011·Musculoskeletal Care·Heidi J SiddlePhilip S Helliwell
Mar 18, 2015·Acta Orthopaedica·Johannes Cornelis SchramaBjørg-Tilde Fevang
Mar 10, 2015·Seminars in Arthritis and Rheumatism·Susan M Goodman
Feb 24, 2009·Best Practice & Research. Clinical Rheumatology·Nick BansbackAslam Anis
Sep 9, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Do-Kyung LeeDae-Hee Lee
Dec 24, 2010·Hand Clinics·Ronald J Anderson
Feb 9, 2018·The Journal of Rheumatology·Susan M Goodman
Dec 3, 2017·The Journal of Rheumatology·Bradley L YoungBrent A Ponce
Sep 17, 2013·The Journal of Rheumatology·Leticia LeonUNKNOWN emAR Study Group
Feb 16, 2012·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Maria A Lopez-OlivoMaria E Suarez-Almazor
May 16, 2014·Spine·Benjamin E SteinKhaled M Kebaish
May 15, 2013·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Susan M Goodman
Sep 6, 2013·Journal of Spinal Disorders & Techniques·Lee M ReichelCharles A Reitman

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