PMID: 11320106Apr 26, 2001Paper

Orthostatic hypotension in elderly persons during passive standing: a comparison with young persons

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
T KawaguchiT Iida

Abstract

The present study was aimed at clarifying the mechanism of orthostatic hypotension (OH) that occurs in elderly persons and at investigating assisting methods to prevent OH by evaluating changes in autonomic nervous system (ANS) activity and cerebral circulation of elderly persons when engaged in passive standing. Eight elderly volunteers and 9 young volunteers gave informed consent to participate in the study. Two experimental conditions were established: (i) "active standing," in which the subjects stood on their own with guidance from an assistant, and (ii) "passive standing," in which the subjects were placed in a standing position completely by an assistant. ANS was determined before and after standing by measuring the heart rate variability. The reaction of the ANS was evaluated on the basis of low-frequency power (LF: 0.05--0.15 Hz) and high-frequency power (HF: 0.15--0.4 Hz), which were separated from the R-R interval data by power spectral analysis using the fast Fourier transformation. Cerebral perfusion was measured over the right frontal region using a near-infrared spectroscopy cerebral oxygen monitor. The main findings were: (i) Transient decreases in blood pressure occurred immediately after standing in both the y...Continue Reading

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Citations

Jul 23, 2003·Pharmacology, Biochemistry, and Behavior·Roy J MathewRobin Davis
Jul 30, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·John E Morley
Oct 15, 2013·Journal of Physiological Anthropology·Emiko MinakuchiTakayasu Kawaguchi
Jul 13, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kannayiram AlagiakrishnanAli Ahmed
Oct 18, 2014·Drugs & Aging·Leah M GoeresDavid S H Lee
Sep 9, 2015·Journal of Medical Systems·Giovanna SanninoLeandro Pecchia
Jan 22, 2014·Journal of Internal Medicine·C AnnweilerO Beauchet
Mar 17, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T YamakiA Hamahata
Feb 17, 2019·European Journal of Applied Physiology·Arjen MolRichard J A van Wezel
Nov 6, 2021·European Journal of Applied Physiology·Jamie J EdwardsJamie M O'Driscoll

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