PMID: 20121687Feb 4, 2010Paper

Oseltamivir-resistant pandemic (H1N1) 2009 influenza in a severely ill patient: the first Australian case

The Medical Journal of Australia
David J SpeersDavid W Smith

Abstract

After a 10-day course of oral oseltamivir for pandemic (H1N1) 2009 influenza infection, a renal transplant recipient developed rapid-onset severe primary viral pneumonia due to oseltamivir-resistant virus. Respiratory failure progressed despite high-dose oral oseltamivir, nebulised zanamivir and cessation of immunosuppressive medications, but his condition improved with intravenous zanamivir. He subsequently died of non-respiratory complications. This is the first case of oseltamivir-resistant pandemic (H1N1) 2009 in Australia and the first report of resistance in a solid organ transplant recipient.

References

Jun 27, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Richard RobsonPenelope Ward
Jun 27, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Svetlana KarieGilbert Deray
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Citations

May 20, 2011·BMC Infectious Diseases·Kristian ThorlundLehana Thabane
Jun 28, 2011·The Journal of Antimicrobial Chemotherapy·L M Thorne-HumphreyUNKNOWN 2009 OPTIMO Study Group
Jan 1, 2010·Frontiers of Medicine in China·Kelvin Kai-Wang ToKwok-Yung Yuen
Oct 18, 2011·Current Opinion in Infectious Diseases·Erhard van der VriesCharles A B Boucher
Jun 29, 2010·Current Opinion in Infectious Diseases·Michael G Ison
Dec 20, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Timothy M UyekiAndrew T Pavia
Aug 28, 2010·The Journal of General Virology·Thomas RoweDavid J Kelvin
Sep 24, 2010·Postgraduate Medicine·Phillip Andrew Reece
Oct 11, 2014·Expert Review of Anti-infective Therapy·Nick SpanakisAthanassios Tsakris
Apr 12, 2012·Clinical Microbiology Reviews·Vincent C C ChengKwok-Yung Yuen
Nov 15, 2013·Influenza and Other Respiratory Viruses·Michael G Ison

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