Osmotic pressure induced pores in phospholipid vesicles.

Biochemistry
C TaupinC Sauterey

Abstract

We report a comparative study of the leadage of hydrophilic molecules from vesicles of egg lecithin (EL) and of dipalmitoyllecithin (DPL). The effect of osmotic pressure differences a leakage is consistent with a model for statistical pore nucleation process. The major difference in osmotic pressure induced leakage from DPL and EL is that the number of pore creation sites is much greater in DPL. We suggest that the difference in number of these sites also accounts for other differences in the properties of DPL and EL, namely for differences in vesicle fusion and apparent rate of "flip-flop".

Citations

Mar 1, 1978·Archives of Microbiology·H R HohlE Wehrli
Nov 22, 1976·The Journal of Membrane Biology·N Bindslev, E M Wright
Dec 1, 1976·The Journal of Membrane Biology·C MillerE Racker
Mar 29, 2011·European Biophysics Journal : EBJ·Gustavo FuertesJesús Salgado
Aug 26, 2006·Medical & Biological Engineering & Computing·C ChenJ A Evans
Jul 17, 2010·Medical & Biological Engineering & Computing·Ravindra P Joshi, Qin Hu
Oct 30, 2012·Cell Biochemistry and Biophysics·Monika Naumowicz, Zbigniew Artur Figaszewski
Oct 5, 1987·Biochimica Et Biophysica Acta·L V ChernomordikY A Chizmadzhev
Jun 6, 2000·Advanced Drug Delivery Reviews·J C WeaverY Chizmadzhev
Feb 9, 2008·Journal of the American Chemical Society·Jinjun ShiPaul S Cremer
Jul 30, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Jia-Yu WangKa Yee C Lee
Dec 1, 2003·Journal of Biological Physics·H G L Coster
Feb 15, 2011·Proceedings of the National Academy of Sciences of the United States of America·Vincent NoireauxAlbert Libchaber
Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·N D Gershon
Oct 10, 1995·Proceedings of the National Academy of Sciences of the United States of America·M A Guedeau-BoudevilleJ M di Meglio
Dec 5, 2000·Molecular Biology of the Cell·T TogoR A Steinhardt
May 31, 1994·Annals of the New York Academy of Sciences·J C Weaver
Sep 17, 2009·The European Physical Journal. E, Soft Matter·R Gerami, R F Bruinsma
Oct 21, 2006·BMC Cell Biology·P Thomas VernierMartin A Gundersen
Nov 5, 2008·Chemical & Pharmaceutical Bulletin·Takayuki YoshidaTakahiro Uchida
May 6, 2006·The Journal of Chemical Physics·J WohlertW J Briels
Dec 2, 2009·The Journal of Chemical Physics·Wouter K den Otter
Apr 3, 2014·Annual Review of Physical Chemistry·Xiaofei XuZhen-Gang Wang
May 2, 2014·Physical Chemistry Chemical Physics : PCCP·Andrea Grafmüller, Volker Knecht
Apr 1, 1993·Journal of Cellular Biochemistry·J C Weaver
Dec 14, 2004·Proceedings of the National Academy of Sciences of the United States of America·Vincent Noireaux, Albert Libchaber
Aug 15, 2014·European Biophysics Journal : EBJ·V F AntonovV Borodulin
Aug 9, 1977·Biochimica Et Biophysica Acta·J D MorrisettA M Gotto
Oct 19, 1979·Biochimica Et Biophysica Acta·C P Tilcock, D Fisher
Jan 30, 2016·Soft Matter·Jaime B HutchisonAnthony D Dinsmore
Jun 7, 2011·Steroids·Monika NaumowiczZbigniew Artur Figaszewski
Nov 10, 2009·Bioelectrochemistry·M S VenslauskasR Rodaite-Riseviciene
Aug 6, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Takayuki YoshidaTakahiro Uchida
Jul 7, 1984·Journal of Theoretical Biology·M M Koslov, V S Markin
Mar 22, 2008·Computational Biology and Chemistry·Krystian Kubica
Jul 23, 2014·The Journal of Membrane Biology·Reuben S SonJames C Weaver
Oct 16, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Xitong Liu, Kai Loon Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.