PMID: 8597860Sep 1, 1995Paper

Ossifying renal tumor of infancy: a clinicopathologic study of nine cases

Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated with the International Paediatric Pathology Association
C Sotelo-AvilaJ E Johnson

Abstract

We studied nine ossifying renal tumors of infancy (ORTI), including all five previously reported cases. There were eight boys and one girl ranging in age from 6 days to 14 months. Gross hematuria was the presenting sign in all nine patients. Eight tumors arose in the left kidney and six in the upper pole. All seven patients with follow-up information were free of recurrence. All lesions were attached to a renal papilla and presented mainly within the calyceal lumen. Two resembled staghorn calculi clinically. All tumors contained varying proportions of osteoid, osteoblastic cells, and spindle cells. The spindle cell component had features strongly suggesting that they represented hyperplastic intralobar nephrogenic rests (ILNR). The proportion of osteoid and degree of osseous maturation increased with increasing age of the patient. ORTI is a distinctive clinicopathologic entity, possibly representing a distinctive interaction between ILNR in the renal papilla with distal collecting duct or urothelial cells in the developing kidney.

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Citations

Sep 10, 2005·Der Radiologe·J-P SchenkJ Tröger
Mar 17, 2004·European Radiology·Michael Riccabona
Sep 15, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jinglan LiuJean-Pierre de Chadarévian
Dec 12, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·L H LoweM Hernanz-Schulman
Jan 11, 2014·Pediatric Radiology·Sang Hwan LeeKyung Chul Moon
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Feb 19, 2013·Journal of Pediatric Surgery·Jimeng HuFan Lv
Dec 15, 2011·Seminars in Roentgenology·Gabriella L Crane, Marta Hernanz-Schulman
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Mar 11, 2016·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ellen M ChungRichard M Conran
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Dec 1, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Benoit VaillancourtDorothée Bouron-Dal Soglio
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Nov 15, 2018·Case Reports in Urology·Ali HajiranMichael Ost
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Mar 1, 1997·Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated with the International Paediatric Pathology Association·A K CharlesC E Keen

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