Osteoarthritis of the ankle after foreign-body reaction to absorbable pins and screws: a three- to nine-year follow-up study

The Journal of Bone and Joint Surgery. British Volume
O Böstman

Abstract

Between 1985 and 1994, 1223 patients with malleolar fractures of the ankle were treated by open reduction and internal fixation with absorbable pins and screws, of whom 74 (6.1%) had an obvious inflammatory foreign-body reaction to the implants. Of these 74, ten later developed moderate to severe osteoarthritis of the ankle despite no evidence of incongruity of the articular surface. The implants used in these patients were made from polyglycolide, polylactide or glycolide-lactide copolymer. The joint damage seemed to be due to polymeric debris entering the articular cavity through an osteolytic extension of an implant track. The ten patients had a long clinical course which included a vigorous local foreign-body reaction, synovial irritation and subsequent degeneration. At a follow-up of three to nine years, ankle arthrodesis had been necessary in two patients and is being considered for another two. The incidence of these changes in the whole series was 0.8%, which is not high, but awareness of this possible late complication is essential.

Citations

Nov 7, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·John K Wildemore, Derek H Jones
Sep 4, 2009·Journal of Materials Science. Materials in Medicine·Tom A P EngelsLeon E Govaert
Nov 10, 2009·Journal of Materials Science. Materials in Medicine·T H SmitL E Govaert
Apr 6, 2000·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·A WeilerN P Südkamp
Jul 24, 2013·International Journal of Biomaterials·Jabr S Al-SanabaniFadhel A Al-Sanabani
Sep 2, 2006·International Orthopaedics·Paul B McKennaTom Burke
Sep 15, 2012·International Orthopaedics·Hanako NishimotoMasahiro Kurosaka
Mar 26, 2003·Journal of Neurosurgery·David W CahillRobert W Engelman
Sep 23, 2010·Expert Opinion on Drug Delivery·Avi SchroederYechezkel Barenholz
Mar 29, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Keishi MarumoDaisaburo Kurosaka
Oct 18, 2005·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yukiharu HasegawaKiyoharu Kawabe
Jul 16, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Shinsuke IshiiMasaki Okuno
Dec 2, 2008·Clinical Oral Implants Research·Z SchwartzB D Boyan
Dec 18, 2013·Journal of Biomedical Materials Research. Part a·Yan LiXiaoping Yang
Jan 24, 2009·Journal of Biomedical Materials Research. Part a·Meng DengCato T Laurencin
May 23, 2003·Foot and Ankle Clinics·Manuel LeyesPedro Guillén
Jun 24, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Eriko MarukawaHiroyuki Harada
Jun 2, 2015·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Attilio BasileAlessio Giai Via
May 21, 2015·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Amirhossein MisaghiAndrew T Pennock
Nov 27, 2002·Journal of Neurosurgery·Jeffrey M TothG Bryan Cornwall
Oct 29, 2002·Orthopedics·P I J M WuismanT H Smit
Sep 12, 2014·Tissue Engineering. Part a·Cheng-Hung ChouShih-Hsin Chang
Jan 3, 2015·Injury·Taher Yousri, Mark Jackson
Sep 8, 2000·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·F A Barber, M A Herbert
Sep 6, 2014·British Medical Bulletin·Ahmed MaganVikas Khanduja
Mar 27, 2009·Foot & Ankle International·Kajetan KlosThomas Mückley
Jan 10, 2003·Journal of Biomaterials Science. Polymer Edition·Kai-Uwe LewandrowskiDebra J Trantolo
Jun 23, 2010·Journal of Biomaterials Science. Polymer Edition·Swaminathan SethuramanCato T Laurencin
Nov 13, 2004·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Karin A Hing
May 25, 2006·Journal of Biomedical Materials Research. Part a·Stephane AunobleJean Charles Le Huec
Feb 9, 2019·Journal of Biomaterials Applications·Narumi OshibeHiroyuki Harada

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